Conventional Radiation Therapy of Gliomas
Assessment of the value of radiation therapy in treatment of the gliomas is difficult. Neurosurgeons and radiation oncologists have had individual opinions regarding the usefulness of radiation therapy and have either given or withheld irradiation accordingly. Until a recent, and as yet unpublished, study of malignant gliomas (1) was initiated, these opinions had never been subjected to the rigors of prospective randomized investigation. Many retrospective analyses have been reported but often details of the surgical and radiation treatments have been omitted. In some reports it is even impossible to ascertain which patients received irradiation. Further compounding the problem is the fact that the natural history, resectability, and responsiveness to irradiation of the various gliomas differ widely.
KeywordsMalignant Glioma Glioblastoma Multiforme Operative Death Irradiate Patient Astrocytoma Grade
Unable to display preview. Download preview PDF.
- 1.The Brain Tumor Study Group (under the auspices of the National Cancer Institute of the National Institutes of Health) Unpublished material.Google Scholar
- 2.BOUCHARD, J.: Textbook of Radiotherapy. 2nd ed., p. 366. G. H. FLET-CHER 6ed.). Philadelphia: Lea & Febiger 1973.Google Scholar
- 3.SHELINE, G. E.: Radiation therapy of central nervous system tumors of childhood. In preparation.Google Scholar
- 5.TAVERAS, J. M., THOMPSON, H. G., Jr., POOL, J. L.: Should we treat glioblastoma multiforme ? Am. J. Roentgenol. Radium Therapy Nucl. Med. 87, 473 (1962).Google Scholar
- 6.KRAMER, S.: Cancer of the central nervous system: Radiation therapy in the management of malignant gliomas. In: Seventh National Cancer Conference Proceedings. American Cancer Society, Inc. 1973.Google Scholar
- 8.DAVIDOFF, L. M.: Thirteen year follow-up study of a series of cases of verified tumors of the brain. Arch. Neurol.Psychiat. 44, 1246 (1940).Google Scholar
- 10.KRICHEFF, I. I., BECKER, M., SCHNECK, S., TAVERAS, J. M.: Intra-cranial ependymomas. A study of survival in 65 cases treated by surgery and irradiation. Am. J. Roentgenol. Radium Therapy Nucl. Med. 91, 167 (1964).Google Scholar
- 11.BOUCHARD, J., PEIRCE, C. B.: Radiation therapy in the management of neoplasms of the central nervous system, with a special note in regard to children: Twenty years’ experience, 1939–1958. Am. J. Roentgenol. Radium Therapy Nucl. Med. 84, 610 (1960).Google Scholar
- 12.BLOOM, H. J. G.: Treatment and prognosis of intracranial tumors in children. Presentation to the 26th Annual Midwinter Radiological Conference, Febr. 2. Los Angeles, Calif.: Los Angeles Radiological Society 1974.Google Scholar
- 13.ABRAMSON, N., RABEN, M., CAVANAUGH, P. J.: Brain tumors in children - analysis of 136 cases. Unpublished presentation to the Radiologic Society of North America, Chicago, Ill., Nov. 1973.Google Scholar