Zusammenfassung
The carcinogenic hazard of heavy exposure of tissues to ionising radiation was clearly recognized within a few years of the first use of roentgen-rays and of the discovery of radioactivity (Frieben, 1902; Porter and White, 1907; Rowntree, 1908). Tumours were seen to develop in areas of skin which had been grossly damaged by irradiation, and the distribution of such tumours over the body surface did not correspond with the usual distribution of skin tumours occurring spontaneously.
This review is based upon analyses undertaken on behalf of the British Medical Research Council.
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Literatur
Andrews, P.: Rodent ulcers induced by X-rays and radium. Univ. of London Thesis for MD, 1957.
Anderson, R. E., Ishida, K.: Malignant lymphoma in survivors of the atomic bomb in Hiroshima. Ann. intern. Med. 61, 853–862 (1964).
Bizzozero, O. J., Johnson, K. G., Ciocco, A., Kawasaki, S., Toyoda, S.: Radiation-related leukaemia in Hiroshima and Nagasaki, 1946- 1964. Ann. intern. Med. 66, 522–530 (1967).
Beach, S. A., Dolphin, G. W.: A study of the relationship between X-ray dose delivered to thyroids of children and the subsequent development of malignant tumours. Phys. med. Biol. 6,583–598 (1962).
Brinkley, D., Haybittle, J. L.: The late effects of artificial menopause by X-radiation. Br. J. Radiol. 42, 519–521 (1969).
Campbell, A., Emery, E. W., Godlee, J. N., Prankerd, T. A. J.: Diagnosis and treatment of primary polycythaemia. Lancet 1, 1074–1077 (1970).
Conard, R. A., Dobyns, B. M., Sutow, W. W.: Thyroid Neoplasia from Radioactive Fallout. J. Amer. med. Ass. 214, 316–324 (1970).
Court-brown, W. M., Doll, R.: Expectation of life and mortality from cancer among British radiol gists. Br. med. J. 2, 181–187 (1958).
Court-Brown, W. M., Doll, R. Mortality from cancer and other causes after radiation therapy for ankylosing spondylitis. Br. med. J. 2, 1327–1332 (1965).
Doll, R.: Age difference in susceptibility to carcinogenesis in man. Br. J. Radiol. 35, 31–36 (1962).
Doll, R. Cancer following therapeutic external irradiation. Paper delivered at 10 th International Cancer Congress, Houston 1970. In course of publication.
Doll, R. Smith, P. G.: The long term effects of X-irradiation in patients treated for metropathia haemorrhagica. Br. J. Radiol. 41, 362–368 (1968).
Dolphin, G. W.: The risk of thyroid cancers following irradiation. Hlth. Phys. 15, 219–228 (1968).
Dolphin, G. W. Eve, I. S.: In: Gastrointestinal radiation injury, pp. 465–476. Ed.: Sullivan, M. F. Amsterdam: Exc. Med. Foundation, 1968.
Doniach, I.: Effects including carcinogenesis of 1311 and X-rays on the thyroid of experimental animals; a review. Hlth. Phys. 9,1357–1362 (1963).
Doniach, I. Experimental thyroidtumours. In: Tumours of the thyroid gland, pp. 73–99. Ed.: Sir David Smithers. Edinburgh & London: E. & S. Livingstone, 1970.
Dublin, L., Spiegelman, M.: Mortality of medical specialists, 1938–1942. J. Am. med. Ass. 137, 1519–1524 (1948).
Evans, R. D.: The effect of skeletally deposited alpha ray emitters in man. Br. J. Radiol. 39, 881–895 (1966).
Frieben, A.: Canceroid nach langdauernder Einwirkung von Röntgenstrahlen. Fortschr. Röntgenstr. 6, 106 (1902).
Goolden, A. W. G.: Radiation Cancer: a review with special reference to radiation tumours in the pharynx, larynx and thyroid. Br. J. Radiol. 30, 626–640 (1957).
Halnan, K. E., Russell, M. H.: Polycythemia Vera, comparison of survival and causes of death in patients managed with and without radiotherapy. Lancet 2, 760–763 (1965).
Hanford, J. M., Quimby, E.H., Frantz, V. K.: Cancer arising many years after radiation therapy. J. Am. med. Ass. 181. 404–410 (1962).
Hasterlik, R. H., Finkel, A. J.: Diseases of bone and joints associated with intoxication by radioactive substances principally radium. Med. Clins. N. Am. 49, 285–296 (1965).
Hempelmann, L. H.: Risk of thyroid neoplasms after irradiation in childhood. Science 160, 159–163 (1968).
Hempelmann, L. H. Pifer, J. F., Burke, G. J., Terry, R., Ames, W. R.: Neoplasms in persons treated in infancy with X-rays for thymic enlargement; report of the 3rd followup survey. J. natn. Cancer Inst. 38, 317–341 (1967).
IAEA Techn. Report 106. The dosimetry and toxicity of thorotrast. Vienna 1968.
IAEA Report of Symposium, Athens 1969. Radiation Induced Cancer. IAEA, Vienna 1969.
International Commission on Radiological Protection, Publication 8. The evaluation of risks from radiation. Oxford: Pergamon Press 1966.
Publication 11. A review of the radiosensitivity of the tissues in bone. Oxford: Pergamon Press 1968
Publication 14. Radiosensitivity and spatial distribution of dose. Oxford: Pergamom Press 1969
Jablon, S., Belsky, J. L.: Radiation induced cancer in atomic bomb survivors. Paper delivered at 10 th International Cancer Congress, Houston 1970. In course of publication.
Lawrence, J. H., Winchell, H. S., Donald, W. G.: Leukaemia in Polycythemia Vera. Ann. intern. Med. 70, 763–771 (1969).
Lewis, E. B.: Leukaemia, multiple myeloma and aplastic anaemia in American radiologists. Science 142, 1492–1494 (1963).
Lundin, F. E., Lloyd, J. W., Smith, E. M., Archer, V. E., Holaday, D. A.: Mortality of uranium miners in relation to radiation exposure, hard- rock minin g and cigarette smoking, 1950 through Sept. 1967. Hlth. Phys. 16, 571–578 (1969).
Mackenzie, I.: Breast cancer following multiple fluoroscopies. Br. J. Cancer 19, 1–8 (1965).
Macmahon, B.: Prenatal X-ray exposure and childhood cancer. J. nat. Cancer Inst. 28, 1173–1191 (1962).
Macmahon, B. Juvenile cancer associated with prenatal irradiation. Paper delivered at 10 th International Cancer Congress, Houston 1970. In course of publication.
Maki, H., Ishimaru, T., Kato, H., Wakabayashi, T.: Carcinogenesis in atomic bomb survivors. Atomic Bomb Casualty Commission Technical Report 24–68 (1968).
Modan, B., Lilienfeld, A. M.: Leukaemogenic effect of ionising radiation treatment in polycythemia. Lancet 2, 439–441 (1964).
Myrden, J. A., Hiltz, J. E.: Breast cancer following multiple flouroscopies during artificial pneumothorax treatment of pulmonary tuberculosis. Can. med. Ass. J. 100, 1032–1034 (1969).
Pochin, E. E.: Long term hazards of radioiodine treatment of thyroid cancer. UICC Monograph Series, Vol. 12, Thyroid Cancer, pp. 293–304. Berlin: Springer-Verlag 1969.
Pochin, E. E. The development of the quantitative bases for radiation protection. Br. J. Radiol. 43, 155–160 (1970).
Porter, C. A., White, C. J.: Multiple carcinomata following chronic X-ray dermatitis. Ann. Surg. 46, 649–671 (1907).
Poston, J.W., Cheka, J. S., Chen, W. L., Fox, W. F., Hubbell, H. H., Jackson, J. E., Jones, T. D., Robinson, E. M., Shinpaugh, W. H., Snyder, W. S., Wagner, E. B.: Dosimetry for human exposures and radiobiology. ORNL-4584, UC-41 Hlth. & Safety, pp. 129–151, 1970.
Raventos, A., Winship, T.: The latent interval for thyroid cancer following irradiation. Radiology 83, 501–508 (1964).
Rowntree, C. W.: Contribution to the study of X-ray carcinoma and the conditions which precede its onset. Archs. Middx. Hosp. 13, 182–205 (1908).
Saccomanno, G., Archer, V. E., Saunders, R. P., James, L. A., Beckler, P. A.: Lung cancer of uranium miners on the Colorado Plateau. Hlth. Phys. 10, 1195–1201 (1964).
Saenger, E. L., Thoma, G. E., Tompkins, E. A.: Incidence of leukaemia following treatment of hyperthyroidism. Preliminary report of the cooperative thyrotoxicosis therapy follow-up study. J. Am. med. Ass.205, 855–862 (1968).
Sampson, R. J., Key, C. R., Buncher, C. R., Iyima, S.: Thyroid carcinoma in Hiroshima and Nagasaki. J. Am. med. Ass. 209, 65–70 (1969).
Socolow, E. L., Hashizuma, A., Neriishi, S., Niitani, R.: Thyroid carcinoma in man after exposure to ionising radiation. New Engl. J. Med. 268, 406–410 (1963).
Spiess, H., Mays, C. W.: Bone cancers induced by 224 Ra (Th X) in children and adults. Paper delivered at 10 th International Cancer Congress, Houston 1970. Health Physics 19, 713–729 (1970).
United Nations Scientific Committee on the Effects of Atomic Radiation. G. A. Off. Rec. 19 th Session, Suppl. No. 14 (A/5814). United Nations, New York 1964.
Wanebo, C. K., Johnson, K. G., Sato, K., Thorsltjnd, T. W.: Breast cancer after exposure to the atomic bombings of Hiroshima and Nagasaki. New Engl. J. Med. 279, 667–671 (1968a).
Wanebo, C. K., Johnson, K. G., Sato, K., Thorsltjnd, T. W. Lung cancer following atomic radiation. Am. rev. resp. Dis. 98, 778–787 (1968b).
Wood, J. W., Tamagaki, H., Neriishi, S., Sato, T., Sheldon, W. F., Archer, P. G., Hamilton, H. B., Johnson, K. G.: Thyroid carcinoma in atomic bomb survivors, Hiroshima and Nagasaki Am. J. Epidemiol.89, 4–14 (1969).
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Pochin, E.E. (1972). Frequency of induction of malignancies in man by ionising radiation. In: Hug, O., Zuppinger, A. (eds) Strahlenbiologie / Radiation Biology. Handbuch der Medizinischen Radiologie / Encyclopedia of Medical Radiology, vol 2 / 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80710-7_8
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