Abstract
The numerous difficulties encountered in evaluating the various immune reactions to insulin (insulin allergy, insulin resistance) under standardized conditions led us to carry out animal experiments. The intention was to produce a delayed immune reaction to insulin and then later to make a more exact study of the humoral antibodies in their varying stages. We hoped to be able to draw conclusions concerning insulin-treated diabetics from these results. The guinea pig was selected as the experimental animal, because this species, in contrast to numerous other kinds of animals, resembles man in its ability to reproduce a florid immune reaction of the delayed type as well as to produce humoral antibodies.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1971 Springer-Verlag Berlin · Heidelberg
About this chapter
Cite this chapter
Federlin, K. (1971). Investigations of the Delayed Immune Reaction and Formation of Antibody to Insulin in Experimental Animals. In: Immunopathology of Insulin. Monographs on Endocrinology, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80608-7_4
Download citation
DOI: https://doi.org/10.1007/978-3-642-80608-7_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-80610-0
Online ISBN: 978-3-642-80608-7
eBook Packages: Springer Book Archive