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DNA Vaccines for Infectious Diseases, Allergies and Cancer

  • Conference paper
Symposium in Immunology VII

Abstract

DNA vaccination involves the direct injection of a suitable designed plasmid DNA molecule into a tissue such that the antigenic proteins encoded by the plasmid are expressed in the cells of the treated host. This extraordinarily simple approach has been translated into practice for many antigens from infectious agents, for putative tumor antigens, and for certain potential allergens. If the results currently obtained in animal models can be replicated with equal efficiency in humans and large animals, and if the justifiable concerns about safety can be resolved, then the DNA vaccination may become the basis for an entirely new generation of vaccines.

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Editors and Affiliations

  1. Institut für Immunologie der Universität Wien, Borschkegasse 8 a, 1090, Wien, Austria

    Martha M. Eibl

  2. Abteilung Hämatologie, Johannes Gutenberg Universität, Langenbeckstr. 1, 55101, Mainz, Germany

    Christoph Huber

  3. Abteilung für Rheumatologie und Klinische Immunologie, Medizinische Universitätsklinik, Hugstetter Str. 55, 79106, Freiburg, Germany

    Hans H. Peter

  4. Pädiatrische Pneumologie und Immunologie, Universitäts-Klinikum Rudolf-Virchow Standort Charlottenburg, Heubnerweg 6, 14059, Berlin, Germany

    Ulrich Wahn

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© 1998 Springer-Verlag Berlin Heidelberg

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Whalen, R.G. (1998). DNA Vaccines for Infectious Diseases, Allergies and Cancer. In: Eibl, M.M., Huber, C., Peter, H.H., Wahn, U. (eds) Symposium in Immunology VII. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80466-3_14

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  • DOI: https://doi.org/10.1007/978-3-642-80466-3_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-63360-0

  • Online ISBN: 978-3-642-80466-3

  • eBook Packages: Springer Book Archive

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