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Perfusion Imaging with Echo-Planar Imaging

  • Chapter
Echo-Planar Imaging

Abstract

The introduction of nuclear magnetic resonance (NMR) into medicine [1] initially created hopes that this totally noninvasive imaging modality would be able to differentiate clearly between healthy and pathological tissue on the basis of T1 and T2 signals [2]. As originally conceived, however, these hopes were overly optimistic as they assumed that parameters characterizing processes on a nuclear or molecular scale could provide a sensitive and specific means of characterizing disease processes which, although ultimately based on molecular derangements, manifest themselves on a micro- and macrostructural and functional level. Thus MRI techniques geared towards elucidating these pathophysiological processes had to be developed.

“Where shall I climb, sound, seek, search, or find that summum bonum which may stay my mind? ... The depth and sea have said ‘tis not in me,’ With pearl and gold it shall not valued be.... It yieldeth pleasures far beyond conceit, And truly beautifies without deceit. Nor strength, nor wisdom, nor fresh youth shall fade, Nor death shall see, but are immortal made. This pearl of price, this tree of life, this spring, Who is possessed of shall reign a king. Nor change of state nor cares shall ever see, But wear his crown unto eternity. This satiates the soul, this stays the mind, And all the rest, hut vanity we find.”

from: The Vanity of All Worldly Things, Anne Bradstreet, ca. 1612–1672

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Authors
  1. M. K. Stehling
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  2. R. Brüning
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  3. B. R. Rosen
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© 1998 Springer-Verlag Berlin Heidelberg

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Stehling, M.K., Brüning, R., Rosen, B.R. (1998). Perfusion Imaging with Echo-Planar Imaging. In: Echo-Planar Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80443-4_13

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  • DOI: https://doi.org/10.1007/978-3-642-80443-4_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-80445-8

  • Online ISBN: 978-3-642-80443-4

  • eBook Packages: Springer Book Archive

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