Genetic Risk Factors of Familial Thrombophilia Play an Important Role in the Early Manifestation of Ischaemic Stroke in Infancy and Childhood

  • H. Vielhaber
  • R. Sträter
  • A. Dübbers
  • G. Kurlemann
  • U. Nowak-Göttl
Conference paper


To determine to what extent genetic risk factors of familial thrombophilia affect the occurrence of childhood stroke, 15 consecutively admitted children with acute ischaemic stroke were investigated. Familial thrombophilia was diagnosed in ii out of 15 patients: factor V Leiden, protein C deficiency and increased lipoprotein (a). Additionally, 12 out of 15 children showed underlying diseases or non-genetic risks. Data of this study indicate that genetic risks of familial thrombophilia play an important role in the etiology of childhood stroke.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • H. Vielhaber
  • R. Sträter
  • A. Dübbers
  • G. Kurlemann
  • U. Nowak-Göttl

There are no affiliations available

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