Skip to main content

Part of the book series: Springer Lab Manual ((SLM))

  • 778 Accesses

Abstract

In electrophysiological or microfluorescence experiments, application of drugs is a necessity when studying receptors gated by these substances. This requires a system allowing local and rapid application of the desired drug. Moreover, when the effects of more than one drug are studied on the same cell, the demands on the system become even more complicated. Most drug application systems are based on a U-tube drug application device. The essential idea of this U-shaped loop is depicted in Fig. 4.1.30

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Bormann J (1992). U-tube drug application. In: Practical electrophysiological methods. Kettenmann H, Grantyn R (eds) Wiley-Liss, New York, pp 136–140

    Google Scholar 

  • Vreugdenhil M (1994). Intrinsic membrane properties of hippocampal pyramidal neurons after kindling epileptogenesis. Ph. D. thesis, University of Amsterdam, The Netherlands

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Dzoljic, M. (1998). A Modified U-Tube Drug Application System. In: Van Duijn, B., Wiltink, A. (eds) Signal Transduction — Single Cell Techniques. Springer Lab Manual. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80368-0_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-80368-0_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-48976-1

  • Online ISBN: 978-3-642-80368-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics