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Infarction, Kidney, Rat, Mouse

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Urinary System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

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Abstract

The gross appearance of renal infarcts is dependent upon their age (Sheehan and Davis 1958).During the first few hours after infarction the lesion is red and the overlying capsule is tense. Thecut surfaces of infarcts are characteristically triangular in shape, with the apex pointing toward the medulla. As the lesion ages, the color changes to gray centrally, and there may be a red rim at the margin. In approximately a week, the lesion becomes depressed below the capsular surface and progressively smaller and firmer. Old infarcts eventually lose their triangular shape and become linear. The size of the infarct is dependent upon the size of the obstructed vessel and the age of the lesion. In cases where there is a recurring embolic shower in the kidney, multiple acute and chronic infarcts may be present in the same animal.

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© 1996 Springer-Verlag Berlin Heidelberg

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Montgomery, C.A. (1996). Infarction, Kidney, Rat, Mouse. In: Jones, T.C., Hard, G.C., Mohr, U. (eds) Urinary System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80335-2_18

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  • DOI: https://doi.org/10.1007/978-3-642-80335-2_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-80337-6

  • Online ISBN: 978-3-642-80335-2

  • eBook Packages: Springer Book Archive

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