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Chronic Progressive Nephropathy, Rat

  • Chapter
Urinary System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

Kidneys of rats with moderate to severe chronic progressive nephropathy (CPN) are enlarged and pale with pitted or granular surfaces (Fig. 194). Small cysts can be visible in the cortex. In advanced disease, kidneys can be enlarged two to three times their normal size. There may also be irregular brown to golden pigmentation radiating from the corticomedullary junction to the surface.

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Authors
  1. Stephen W. Barthold
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Editors and Affiliations

  1. Harvard Medical School, ILSI Research Foundation, 1126 Sixteenth Street,N.W., Washington, DC, 20036, USA

    Thomas Carlyle Jones D.V.M., D.Sc. (Professor of Comparative Pathology Emeritus) (Professor of Comparative Pathology Emeritus)

  2. American Health Foundation, One Dana Drive, Valhalla, NY, USA

    Gordon C. Hard BVSc., Ph.D., DSc., FRCPath., FRCVS, FAToxSci. (Director of Administration and Senior Toxicologist) (Director of Administration and Senior Toxicologist)

  3. Medizinische Hochschule Hannover, Institut für Experimentelle Pathologie, Konstanty-Gutschow-Strasse 8, 30625, Hannover, Germany

    Ulrich Mohr M.D. (Professor of Experimental Pathology) (Professor of Experimental Pathology)

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© 1998 Springer-Verlag Berlin Heidelberg

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Barthold, S.W. (1998). Chronic Progressive Nephropathy, Rat. In: Jones, T.C., Hard, G.C., Mohr, U. (eds) Urinary System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80335-2_17

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  • DOI: https://doi.org/10.1007/978-3-642-80335-2_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-80337-6

  • Online ISBN: 978-3-642-80335-2

  • eBook Packages: Springer Book Archive

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