Summary
Between 1988 and 1995 we treated ten patients aged 7–18 years for familial MTC or MEN II syndrome with a total of 17 operations. Using these surgical procedures, 6/9 patients remained free of tumor after 0–8 years (mean 4.5 years).
In conclusion, we recommend thyroidectomy [1] in children younger than 5 years of age and a family history of MEN IIa; [2] in children younger than 3 years of age, presenting the characteristic phenotype of MEN IIb, both with a positive test for mutation of the RET protooncogene [4].
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© 1996 Springer-Verlag Berlin Heidelberg
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Schäfer, K., Senninger, N., Roth, H., Buhr, H.J. (1996). Chirurgisches Vorgehen bei Kindern mit medullärem Schilddrüsenkarzinom unter Berücksichtigung der multiplen endokrinen Neoplasie Typ II. In: Hartel, W. (eds) Wahrung des Bestandes, Wandel und Fortschritt der Chirurgie. Langenbecks Archiv für Chirurgie, vol 1996. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80295-9_46
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DOI: https://doi.org/10.1007/978-3-642-80295-9_46
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