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Photodynamic Therapy of B16 Pigmented Melanoma with Si(IV)Naphthalocyanine Photoactivated by Diode Laser

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Laser in der Medizin / Laser in Medicine

Abstract

Melanotic malignant melanoma represents a major cause of death among skin neoplasias and its incidence is steadily increasing in Western world probably owing to changes in lifestyle which favour brief but intense exposures to sunlight, as well as due to enhanced levels of UV-B reaching the earth surface (1,2). White surgery is still the elective treatment for melanoma, alternative methods, including radiotherapy or immunotherapy, give a generally poor outcome (3).

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References

  1. Liotta L.A., Guirguis R., Stracke M. “Biology of melanoma invasion and metastasis” Pigment Cell Res. 1: 5–15 (1982)

    Google Scholar 

  2. Moan J., Dahlback A. “Ultraviolet radiation and skin cancer: epidemiological data from Scandinavia” In: Environmental UV Photobiology (Young A.R. et al., eds.), Plenum Press, New York, pp. 255–293 (1993)

    Google Scholar 

  3. Balch M.C., Milton G.W., Shaw H.M., Soong S.J. Cutaneous melanoma: clinical mamagement and treatment worldwide, J.B. Lippincott, Philadelphia, pp. 388–466 (1985)

    Google Scholar 

  4. Polla L.L., Margolis R.J., Dover J.S., Whitaker D., Murphy G.F., Jacques S.L., Anderson R.R. “Melanosomes are a primary target of Q-switched ruby laser irradiation in Guinea pig skin” J. Invest. Dermatol. 89: 281–286 (1982)

    Article  Google Scholar 

  5. Biolo R., Jori G., Soncin M., Pratesi R., Vanni U., Rihter B., Kenney M.E., Rodgers M.A.J. “Photodynamic therapy of B16 pigmented melanoma with liposome-delivered Si(IV)- naphthalocyanine” Photochem. Photobiol. 59: 362–363 (1994)

    Article  Google Scholar 

  6. Jori G. “In vivo transport and pharmacokinetic behaviour of tumour photosensitizers” In: Photosensitizing Compounds: Their Chemistry, Biology and Clinical Use (Bock G.G., Harnett S., eds.) Wiley, Chichester, Ciba Foundation Symposium 146, pp. 78–94 (1989)

    Google Scholar 

  7. Jori G., Reddi E. “The role of lipoproteins in the delivery of tumor-targeting photosensitizers” Int. J. Biochem. 25: 1363–1375 (1993)

    Article  Google Scholar 

  8. Cecchetti W., Biolo R., Jori G. “Laser diode coupled with optical fiber for applications in photodynamic therapy” Technol. Health Care 1: 219–222 (1994)

    Google Scholar 

  9. Reddi E., Zhou C., Biolo R., Menegaldo E., Jori G. “Liposome- or LDL-administered Zn(II)- phthalocyanine as a photodynamic agent for tumours. I. Pharmacokinetic properties and phototherapeutic efficiency” Br. J. Cancer 61: 407–411 (1990)

    Article  Google Scholar 

  10. Jori G. “Far-red absorbing photosensitizers: their use in the photodynamic therapy of tumours” J. Photochem. Photobiol., B.Biol. 62: 371–378 (1992)

    Article  Google Scholar 

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© 1996 Springer-Verlag, Berlin Heidelberg

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Schaffer, M. et al. (1996). Photodynamic Therapy of B16 Pigmented Melanoma with Si(IV)Naphthalocyanine Photoactivated by Diode Laser. In: Waidelich, W., Staehler, G., Waidelich, R. (eds) Laser in der Medizin / Laser in Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80264-5_15

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  • DOI: https://doi.org/10.1007/978-3-642-80264-5_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-61318-3

  • Online ISBN: 978-3-642-80264-5

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