Abstract
Several studies have shown acamprosate to increase abstinence rates in weaned alcoholics compared to placebo. This makes the substance a promising “anticraving” drug of high clinical importance (Paille et al. 1995; Soyka, this volume; H. Sass, M. Soyka, K. Mann, W. Zieglgänsberger 1995, Relapse Prevention by Acamprosate: Results from a Placebo Controlled Study in Alcohol Dependence, in press).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Baschek I-L, Bredenkamp J, Oehrle B, Wippich W (1977) Bestimmung der Bildhaftigkeit (I), Konkretheit (C) and der Bedeutungshaltigkeit (m’) von 800 Substantiven. Z Exp Ang Psychol 24: 353–396
Collingridge GL, Bliss TVP (1987) NMDA receptors–their role in long-term potentiation. Trends Neurosci 10: 288–293
Ehlers CL, Kaneko WM, Wall TL, Chaplin RI (1992) Effects of dizocilpine (MK-801) and ethanol on the EEG and event-related potentials ( ERPs) in rats. Neuropharmacology 31: 369–378
Handelmann GE, Contreras PC, O’Donohue TL (1987) Selective memory impairment by phencyclidine in rats. Eur J Pharmacol 140: 69–73
Lawlor BA, Davis KL (1992) Does modulation of glutamatergic function represent a viable therapeutic strategy in Alzheimer’s disease? Biol Psychiatry 31: 337–350
McEntee WJ, Crook TH (1993) Glutamate: its role in learning, memory, and the aging brain. Psychopharmacology 111: 391–401
McLamb RL, Williams LR, Nanry KP, Wilson WA, Tilson HA (1990) MK-801 impedes the acquisition of a spatial memory task in rats. Pharmacol Biochem Behav 37: 41–45
Morris RGM, Anderson E, Lynch GS, Baudry M (1986) Selective impairment of learning and blockade of long-term potentiation of an N-methyl-D-aspartate receptor antagonist, AP5. Nature 319: 774–776
Paille FM, Guelfi JD, Perkins AC, Royer RJ, Steru L, Parot P (1995) Double-blind randomized multicenter trial of acamprosate in maintaining abstinence from alcohol. Alcohol Alcohol 30: 239–247
Warburton DM, Rusted JM (1989) Memory assessment. In: Hindmarch I, Stonier PD (eds) Human psychopharmacology: measures and methods, volt Wiley, New York, pp 155–178
Wozniak DF, Olney JW, Kettinger L III, Price M, Miller JP (1990) Behavioral effects of MK-801 in the rat. Psychopharmacology 101: 47–56
Zeise ML, Kasparow S, Capogna M, Zieglgänsberger W (1993) Acamprosate (calciumhomotaurinate) decrease postsynaptic potentials in the rat neocortex: possible involvement of excitatory amino acid receptors. Eur J Pharmacol 231: 47–52
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1996 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Kathmann, N., Soyka, M., Gallinat, J., Hegerl, U. (1996). Effects of Acamprosate on Verbal Learning in Healthy Young Subjects. In: Soyka, M. (eds) Acamprosate in Relapse Prevention of Alcoholism. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80193-8_7
Download citation
DOI: https://doi.org/10.1007/978-3-642-80193-8_7
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-80195-2
Online ISBN: 978-3-642-80193-8
eBook Packages: Springer Book Archive