Abstract
The major histocompatibility complex (MHC) of the typical mammal is a very large genetic region that encodes many molecules of different structures and functions. However, the MHC was discovered and is presently defined by the presence of two multigene families with some highly polymorphic (that is, multiallelic) members. These encode the so-called classical class I and class II cell surface glycoproteins that bind antigenic peptides and present them for specific recognition by T lymphocytes of the immune system (reviewed in Klein 1986; Lawlor et al. 1990).
Keywords
- Major Histocompatibility Complex
- Major Histocompatibility Complex Molecule
- Major Histocompatibility Complex Gene
- Rous Sarcoma Virus
- Infectious Pathogen
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References
Auer H, Mayr B, Lambrou M, Schleger W (1987) An extended chicken karyotype, including the NOR chromosome. Cytogenet Cell Genet 45: 218–221
Bloom S, Bacon L (1985) Linkage of the major histocompatibility ( B) complex and the nucleolar organizer region in the chicken. J Heredity 76: 146–154
Bloom SE, Briles WE, Briles RW et al. (1987) Chromosomal localization of the major histocompatibility (B) complex ( MHC) and its expression in chickens aneuploid for the major histocompatibility complex/ribosomal deoxyribonucleic acid microchromosome. Poult Sci 66: 782–789
Briles WE, Stone H, Cole R (1977) Marek’s disease: effect of B histocompatibility alloalleles in resistant and susceptible chicken lines. Science 195: 193–195
Briles WE, Briles RW, Stone HA (1983) Resistance to a malignant lymphoma in chicken is mapped to a subregion of the major histocompatibility ( B) complex. Science 219: 977–979
Bumstead N, Palyga J (1992) A preliminary linkage map of the chicken genome Genomics 13: 690–697
Campbell RD, Trowsdale J (1993) The human MHC. Immunol Today 14: 349
Christidis L (1990) Ayes, In: John B (ed) Animal cytogenetics, vol 4138. Borntraeger, Berlin, pp 1–116
Crittenden L, Muhm R, Burmester B (1972) Genetic control of susceptibility to avian leukosis complex. 2. Marek’s disease. Poult Sci 51: 261–267
Crone M, Simonsen M (1987) Avian major histocompatibility complex: a birds eye view. In: Toivanen A. Toivanen P (eds) Avian immunology: basis and practice, vol 2. CRC Press, Boca Raton FL, pp 25–42
Dietert R, Taylor R, Dietert M (1990) The chicken Major Histocompatibility complex: structure and impact on immune function, disease resistance and productivity. In: Basta O (ed) MHC, differentiation antigens and cytokines in animals and birds. Monographs in animal immunology, vol 1. Barlab. Backsburg VA, pp 7–26
Falk K, Rotzschke O (1993) Consensus motifs and peptide ligands of MHC class I molecules. Semin Immunol 5: 81
Gallatin W, Longenecker B (1979) Expression of genetic resistance of an oncogenic herpesvirus at the target level. Nature 280: 587–589
Göbel T, Chen C-L, Lahti J, Kubota T, Kuo C-L, Aebersold R, Hood L, Cooper M (1994) Identification of T-cell receptor a-chain genes in the chicken. Proc Natl Acad Sci USA 91: 1094–1098
Goto R, Miyada C, Young S, Wallace R, Abplanalp H, Bloom S, Briles W, Miller M (1988) Isolation of a cDNA clone from the B-G subregion of the chicken histocompatibility ( B) complex. Immunogenetics 27: 102–109
Guillemot F, Billault A, Pourquie O, Behar G, Chausse A-M, Zoorob R, Kreiblich G, Auffray C (1988) A molecular map of the chicken major histocompatibility complex: the class II 13 genes are closely-linked to the class I genes and the nucleolar organizer. EMBO J 7: 2775–2785
Hala K, Vilhelmova M, Hartmanova J (1976) Probable crossing-over in the B blood group of chickens. Immunogenetics 3: 97–103
Hill AVS, Allsopp C, Kwiatowski D, Antsey N, Twumasi P, Rowe A, Bennet S, Brewster D, McMichael A, Greenwood B (1991) Common West African HLA antigens are associated with protection from severe malaria. Nature 352: 595–600
Holmquist G (1989) Evolution of chromosome bands: molecular ecology of noncoding DNA. J Mol Evol 28: 469–486
Kaufman J, Salomonsen J (1993) What in the dickens is with those chickens? Res Immunol 144: 495–519
Kaufman J, Salomonsen J, Skjødt K (1989) B-G cDNA clones have multiple small repeats and hybridize to both chicken MHC regions. Immunogenetics 30: 440–451
Kaufman J, Salomonsen J, Riegert P, Skjødt K (1991a) Using chicken class I sequences to understand how xenoantibodies crossreact with MHC-like molecules in nonmammalian vertebrates. Am Zool 31: 570–579
Kaufman J, Skjødt K, Salomonsen J (1991b) The B-G multigene family of the chicken MHC. Crit Rev Immunol 11: 113–143
Kaufman J, Andersen R, Avila D, Engberg J, Lambris J, Salomonsen J, Welinder K, Skjødt K (1992) Different features of the MHC class I heterodimer have evolved at different rates: chicken B-F and β2 microglobulin sequences reveal invariant surface residues. J Immunol 148: 1532–1546
Kaufman J, Bumstead N, Miller M, Riegert P, Salomonsen J (1995a) The chicken class II α gene is located outside of the B complex. In: Davison TF, Bumstead N, Kaiser P (eds) Advances in avian immunology. Carfax, Abingdon, UK, pp 119–127
Kaufman J, Völk H, Wallny H-J (1995b) A “minimal essential MHC” and an “unrecognized MHC”: two extremes in selection for polymorphism. Immunol Rev 143: 63–88
Klein J (1986) Natural history of the major histocompatibility complex. Wiley, New York
Klein J (1987) Origin of major histocompatibility complex polymorphism: the trans-species hypothesis. Hum Immunol 19: 155–162
Koch C, Skjoedt K, Toivanen A, Toivanen P (1983) New recombinants within the MHC ( B-complex) of the chicken. Tissue Antigens 21: 129–137
Lawlor D, Zemmour J, Ennis P, Parnam P (1990) Evolution of class I MHC genes and proteins: from natural selection to thymic selection. Annu Rev Immunol 8: 23–64
Miller MM, Goto R, Zoorob R, Auffray C, Briles WE (1994a) Regions of homology shared by Rfp-Y and major histocompatibility B complex genes. Immunogenetics 39: 71–73
Miller MM, Goto R, Bernot A, Zoorob R, Auffray C, Bumstead N, Briles WE (1994b) Two MHC class I and two MHC class II genes map to the chicken Rfp-Y system outside the B complex. Proc Natl Acad Sci USA 91: 4397–4401
Moretta L, Ciccone E, Moretta A, Höglund P, Öhlen C, Kärre K (1992) Allorecognition by NK cells: nonself or no self? Immunol Today 13: 300–306
Pazderka F, Longenecker B, Law G, Stone H, Ruth R (1975) Histocompatibility of chicken populations selected for resistance to Marek’s disease. Immunogenetics 2: 93–100
Pink JRL, Croege W, Hala K, Miggiano VC, Ziegler A (1977) A threelocus model for the chicken major histocompatibility complex. Immunogenetics 5: 203–216
Plachy J, Pink JRL, Hala K (1992) Biology of the chicken MHC ( B complex ). Crit Rev Immunol 12: 47–79
Potts W, Wakeland E (1993) Evolution of MHC genetic diversity: a tale of incest, pestilence and sexual preference. Trends Genet 9: 408
Reynaud C-A, Anquez V, Grimal H, Weill J-C (1987) A hyperconversion mechanism generates the chicken light chain preimmune repertoire. Cell 48: 379–388
Reynaud C-A, Dahan A, Anquez V, Weill J-C (1989) Somatic hyperconversion diversifies the single VH gene of the chicken with a high incidence in the D region. Cell 59: 171–183
Riegert P, Andersen R, Bumstead N, Döhring C, Dominguez-Steglich M, Engberg J, Salomonsen J, Schmidt M, Skjedt K, Schwager J, Kaufman J (1996) The chicken 132 microglobulin gene is located on a non-MHC microchromosome: a small G + C rich gene with X and Y boxes in the promoter. Proc Nati Acad Sci USA (in press)
Schat K (1987) Immunity in Marek’s disease and other tumors. In: Toivanen A, Toivanen P (eds) Avian immunolgy: basis and practice, vol 2. CRC Press, Boca Raton FL, pp 101–128
Schwartz D, Tizard R, Gilbert W (1983) Nucleotide sequence of Rous Sarcoma virus. Cell 32: 853
Sharma JM, Okazaki W (1981) Natural killer cell activity in chickens: target cell analysis and effect of antithymocyte serum on effector cells. Infect Immun 31: 1078
Shields G (1982) Comparative avian cytogenetics: a review. Condor 84: 45–58
Simonsen M, Crone M, Koch C, Hala K (1982) The MHC haplotypes of the chicken. Immunogenetics 16: 513–532
Tegelström H, Ebenhard T, Ryttman H (1983) Rate of karyotype evolution and speciation in birds. Hereditas 98: 235–239
Tjoelker L, Carlson L, Lee K, Lahti J, McCormack W, Leiden J, Chen CL, Cooper M, Thopson C (1990) Evolutionary conservation of antigen recognition: the chicken T-cell receptor ß chain. Proc Natl Acad Sci USA 87: 7856–7860
Trowsdale J (1993) Genomic structure, function in the MHC. Trends Genet 9: 117–122
Trowsdale J (1995) “Both man and bird and beast”: comparative organization of MHC genes. Immunogenetics 41: 1–17
Zoorob R, Bernot G, Renoir DM, Choukri F, Auffray C (1993) Chicken major histocompatibility complex class II B genes: analysis of interallelic and inter-locus sequence variance. Eur J Immunol 23: 1139–1145
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© 1996 Springer-Verlag Berlin Heidelberg
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Kaufman, J., Wallny, H.J. (1996). Chicken MHC Molecules, Disease Resistance and the Evolutionary Origin of Birds. In: Vainio, O., Imhof, B.A. (eds) Immunology and Developmental Biology of the Chicken. Current Topics in Microbiology and Immunology, vol 212. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80057-3_12
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DOI: https://doi.org/10.1007/978-3-642-80057-3_12
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