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Immunology and Developmental Biology of the Chicken pp 129–141Cite as

Chicken MHC Molecules, Disease Resistance and the Evolutionary Origin of Birds

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 212))

Abstract

The major histocompatibility complex (MHC) of the typical mammal is a very large genetic region that encodes many molecules of different structures and functions. However, the MHC was discovered and is presently defined by the presence of two multigene families with some highly polymorphic (that is, multiallelic) members. These encode the so-called classical class I and class II cell surface glycoproteins that bind antigenic peptides and present them for specific recognition by T lymphocytes of the immune system (reviewed in Klein 1986; Lawlor et al. 1990).

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Author information

Author notes

  1. H. J. Wallny

    Present address: Biotest Pharma GmbH, Landsteiner Str. 5, 63303, Dreieich, Germany

Authors and Affiliations

  1. Basel Institute for Immunology, Grenzacherstrasse 487, 4005, Basel, Switzerland

    J. Kaufman & H. J. Wallny

Authors
  1. J. Kaufman
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  2. H. J. Wallny
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Editors and Affiliations

  1. Basel Institute for Immunology, Grenzacherstr. 487, 4005, Basel, Switzerland

    Olli Vainio M.D.  & Beat A. Imhof Ph.D.  & 

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© 1996 Springer-Verlag Berlin Heidelberg

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Kaufman, J., Wallny, H.J. (1996). Chicken MHC Molecules, Disease Resistance and the Evolutionary Origin of Birds. In: Vainio, O., Imhof, B.A. (eds) Immunology and Developmental Biology of the Chicken. Current Topics in Microbiology and Immunology, vol 212. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80057-3_12

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  • DOI: https://doi.org/10.1007/978-3-642-80057-3_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-80059-7

  • Online ISBN: 978-3-642-80057-3

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