Abstract
The human minisatellite D7S22 (probe g3) is extremely polymorphic (heteroz. freq. 97%) with a paternal mutation rate estimated at 1.4% (Stenersen et al. 1994).The size distribution of g3 alleles (fig. 1) reveals some size clustering of alleles. The smallest alleles (0–2 kb) show comparably reduced allelic diversity with one common small allele (14 repeats, freq 12.5%, Andreassen and Olaisen, 1994). No mutated 14 repeat alleles were found in a material with 2808 father-child observations, indicating that this allele has a reduced mutation rate.
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© 1996 Springer-Verlag Berlin Heidelberg
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Andreassen, R., Olaisen, B. (1996). Mutation rate variation in the hypervariable VNTR g3 (D7S22) is associated with a flanking DNA sequence polymorphism near the repeat array. In: Carracedo, A., Brinkmann, B., Bär, W. (eds) 16th Congress of the International Society for Forensic Haemogenetics (Internationale Gesellschaft für forensische Hämogenetik e.V.), Santiago de Compostela, 12–16 September 1995. Advances in Forensic Haemogenetics, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80029-0_42
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