Automated Analysis of 5 STR Loci: Allele Frequencies and Family Studies in the German Population
Analysis of polymorphic DNA loci by the polymerase chain reaction (PCR) technique is a very powerful tool not only in the field of criminal investigation but also in paternity testing. Compared to VNTR systems typed by Southern Blot hybridisation, STR elements offer considerable advantages concerning sensitivity, precision and reproducibility of fragment size estimates and biomathematical evaluation.
KeywordsDiscrimination Power Paternity Testing Allelic Ladder Paternity Case Fluorescent Polymerase Chain Reaction
Unable to display preview. Download preview PDF.
- Schmitter H., Sonntag M.-L. (1995). Proposal for general rules for the denominations of alleles of STR-loci based on the electrophoretic mobilities of their fragments. Klin. Lab. 41: 173–176Google Scholar