Abstract
As a science, toxicology defines the interaction between chemical and/or physical agents and the consequences of the alterations to living tissues, cells, and intact organisms. Another purpose for the study of these biological consequences is to delineate and understand the risk to humans and animals from exposure, either intentionally or accidentally, and to prevent the consequences of that biological-agent interaction.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Albini, A., Iwamoto, Y., Kleinman, H.K., Martin, G.R., Aaronson, S.A., Kozlowski, JM, McEwen, RN,(1987) A rapid in vitro assay for quanitating the invasive potential of tumor cells. Cancer Res., 47: 3239–3245
Frazier, J.F.,(1989) Scientific Criteria for Validation of In Vitro Toxicity Tests., OECD Publications, Paris.
Goldberg, A.,Silber, P., (1992) Status of In Vitro Ocular Irritation Testing, Lens and Eye Toxicity Research, 9 (3&4), 151–192
Goldberg, A., Frazier, J., Bruick, D., Dickens, M., Flint, O., Gettings, S., Hill, R., Lipnick, R., Renskers, K., Bradlaw, J., Scala, R., Veronesi, B., Green, S., Wilcox, N. and Curren, R. (1993), Framework for Validation and Implementation of In Vitro Toxicity Tests: Report of the Validation and Technology Transfer Committee of the Johns Hopkins Center for Alternatives to Animal Testing, Journal of the American College of Toxicology, Vol. 12, No. 1
Koeter, H.,(1993) International Acceptance of In Vitro Testing, Proceedings of the Symposium: Current Trends: In Vitro Toxicology and Eye Irritancy Testing, J.F. Morgan Research Foundation.
National Academy of Science (1984)- Toxicity Testing, Strategies to Determine Needs and Priorities, National Academy Press, Washington, DC,
Penno, M.B., De Maio, A., (1992) A murine model for evaluating metastatic potential: Characterization of a 90–110 kDa metastasis binding protein. Exper. Geront. 27: 493–501.
Wei Q., Matanoski, G.M., Farmer, E.F., Hedayati, M.A. and Grossman, L., (1993) DNA Repair and Aging in Basal Cell Carcinoma: A molecular Epidemiology Study. Proc. Nat’l. Academy Science, USA, 90: 1614–1618.
Wei, Q, Matanoski, G.M., Farmer, E.R., Hedayati, M.A. and Grossman, L. (1994) DNA Repair: a potential market for cancer susceptibility. Cancer Bull. 46: 233–237.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Goldberg, A.M. (1995). Modulation of Cellular Responses in Toxicity. In: Galli, C.L., Marinovich, M., Goldberg, A.M. (eds) Modulation of Cellular Responses in Toxicity. NATO ASI Series, vol 93. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79872-6_1
Download citation
DOI: https://doi.org/10.1007/978-3-642-79872-6_1
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-79874-0
Online ISBN: 978-3-642-79872-6
eBook Packages: Springer Book Archive