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Structure and modifications of the junior chaperone α-crystallin

From lens transparency to molecular pathology

  • Chapter
EJB Reviews 1994

Part of the book series: EJB Reviews 1994 ((EJB REVIEWS,volume 1994))

Abstract

α-Crystallin is a high-molecular-mass protein that for many decades was thought to be one of the rare real organ-specific proteins. This protein exists as an aggregate of about 800 kDa, but its composition is simple. Only two closely related subunits termed αA- and αB-crystallin, with molecular masses of approximately 20 kDa, form the building blocks of the aggregate.

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Abbreviations

HSP:

heat-shock protein

FAB:

fast-atom-bombardment.

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  1. Department of Biochemistry, University of Nijmegen, P. O. Box 9101, NL-6500 HB, Nijmegen, The Netherlands

    Patricia J. T. A. Groenen, Karin B. Merck, Wilfried W. De Jong & Hans Bloemendal

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Groenen, P.J.T.A., Merck, K.B., De Jong, W.W., Bloemendal, H. (1994). Structure and modifications of the junior chaperone α-crystallin. In: EJB Reviews 1994. EJB Reviews 1994, vol 1994. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79502-2_13

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