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Selective Encapsidation of Adenovirus DNA

  • Chapter
The Molecular Repertoire of Adenoviruses I

Part of the book series: Current Topics in 199/I Microbiology and Immunology ((CT MICROBIOLOGY,volume 199/1))

Abstract

The selective packaging of adenovirus DNA into a capsid raises a number of interesting questions. How is the viral DNA specifically selected from the pool of viral and cellular DNA for encapsidation? What protein-protein and protein-DNA interactions are involved in this process? Are cellular proteins involved in adenovirus packaging? Is the packaging process coordinated with viral DNA replication? Does the virus share a packaging mechanism with one or more of the well-characterized prokaryotic phages? The focus of this review will be on the specific cis-acting elements that direct the selective encapsidation of adenovirus DNA into virions at late times after infection and the potential viral proteins that may be involved in this process.

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Author information

Authors and Affiliations

  1. Department of Molecular Genetics and Microbiology, Health Sciences Center, State University of New York, Stony Brook, NY, 11794, USA

    S. I. Schmid & P. Hearing

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  1. S. I. Schmid
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  2. P. Hearing
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Editors and Affiliations

  1. Institut für Genetik, Universität zu Köln, Weyertal 121, 50931, Köln, Germany

    Walter Doerfler  & Petra Böhm  & 

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© 1995 Springer-Verlag Berlin Heidelberg

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Schmid, S.I., Hearing, P. (1995). Selective Encapsidation of Adenovirus DNA. In: Doerfler, W., Böhm, P. (eds) The Molecular Repertoire of Adenoviruses I. Current Topics in 199/I Microbiology and Immunology, vol 199/1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79496-4_5

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  • DOI: https://doi.org/10.1007/978-3-642-79496-4_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79498-8

  • Online ISBN: 978-3-642-79496-4

  • eBook Packages: Springer Book Archive

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