Ex Vivo and in Vitro Models in Acetaminophen Hepatotoxicity Studies. Relationship between Glutathione Depletion, Oxidative Stress and Disturbances in Calcium Homeostasis and Energy Metabolism
The hepatotoxicity of acetaminophen (APAP) seems to be linked to several biochemical perturbations such as glutathione depletion, oxidative stress, Ca2+ homeostasis disturbances and/or changes in energy metabolism.
KeywordsPermeability HPLC Glutathione Carbon Monoxide Disulfide
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