multiple cystic lesions in white matter without clinical manifestations (unidentified black holes)
We report three patients with normal daily life and normal professional or school activities who were submitted for cerebral MRI studies owing to minor symptoms. MRI showed multiple and wide lesions in one or both hemispheres which were iso-intense relative to cerebrospinal fluid on all pulse sequences. No convincing clinical or laboratory evidence was found to explain the exact nature of these lesions. The possibility of dilated Virchow-Robin spaces (VRS) seems too simplistic because of the size and shape, specifically of the unilateral lesions, which are not usual characteristics of VRS.
key wordsVirchow-Robin spaces Brain abnormalities Magnetic resonance imaging
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