The radiology of progressive multifocal leukoencephalopathy
Progressive multifocal leukoencephalopathy (PML) is a progressive multifocal disease of the brain secondary to an opportunistic viral infection that primarily affects immunosuppressed patients. Fifty-five to 85% of PML cases are directly attributable to the acquired immunodeficiency syndrome. The neuroimaging findings of PML parallel the pathologic changes and have a variable appearance on CT and MRI. The features are nonspecific and can mimic a wide spectrum of pathologic states.
Key wordsProgressive multifocal leukoencephalopathy Acquired immunodeficiency syndrome Demyelinating disease
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