Pathogenetic Mechanisms in Gram-Positive Shock: Studies on the Ability of Streptococcus pyogenes to Induce Nitric Oxide In Vitro

  • P. Mills
  • T. Evans
  • J. Cohen
Conference paper


Sepsis and its sequelae are a cause of significant morbidity and mortality worldwide. Septic shock is a clinical syndrome that has become increasingly important in the past 40 years (Glauser et al. 1991) and has been increasing in incidence since the early part of this century (Parrillo et al. 1990; Billiau and Vandekerckhove 1991). Much work has been conducted in elucidating the pathogenic mechanisms responsible for the deleterious effects seen in this condition.


Nitric Oxide Septic Shock Toxic Shock Syndrome Tumour Necrosis Factor Production Streptococcal Toxic Shock Syndrome 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • P. Mills
  • T. Evans
  • J. Cohen

There are no affiliations available

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