The Hemopump: Clinical Results and Future Applications

  • W. Aboul-Hosn
  • R. Wampler


Cardiovascular disease is the leading cause of death in the United States [1], killing about one million Americans (population 250 million) each year. Seventy million Americans suffer from and nearly two people in five will ultimately die of cardiovascular disease. Acute myocardial infarction kills 500 000 Americans each year and of these, 90000 die of cardiogenic shock. Table 1 shows the number of deaths associated with cardiovascular disease and myocardial infarction in the United States.


Cardiogenic Shock Pulmonary Capillary Wedge Pressure Centrifugal Pump Circulatory Support Acute Myocardial Infraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    American Heart Association (1993) Heart and stroke facts statistics. American Heart Association Press, Dallas, TexasGoogle Scholar
  2. 2.
    Rutan P, Rountree W, Myers K, Baker L (1989) Initial experience with the hemopump J Crit Care Nursing North Am 1(3):527–534Google Scholar
  3. 3.
    Norman JC, Cooley DA, Igo SR et al. (1977) Prognostic indices for survival during postcardiotomy intra-aortic balloon pumping. J Thorac Cardiovasc Surg 74(5):709–720PubMedGoogle Scholar
  4. 4.
    Parmley W (1983) Cardiac failure. In: Rosen MR, Hoffman BF (eds) Cardiac therapy. Nijhoff, Boston pp 21–44CrossRefGoogle Scholar
  5. 5.
    Shoemaker WC, Bland RD, Appel PL (1985) Therapy of critically ill postoperative patients based on outcome prediction and prospective clinical trials. Surg Clin North Am 65:811–833PubMedGoogle Scholar
  6. 6.
    Schoen FJ, Palmer DC, Bernhard WF et al. (1986) Clinical temporary ventricular assist. J Thorac Cardiovasc Surg 92:1071–1081PubMedGoogle Scholar
  7. 7.
    Lass J, Campbell CD, Takanashi Y, Pick R, Replogle RL (1979) Preservation of ischemic myocardium with TALVB using complete left ventricular decompression. Trans Am Soc Artif Intern Organs 25:220–223Google Scholar
  8. 8.
    Takanashi Y, Campbell CD, Laas J, Pick RL, Meus P, Replogle RL (1981) Reduction of myocardial infarct size in swine: a comparative study of intraaortic balloon pumping and transapical left ventricular bypass. 32:475–485Google Scholar
  9. 9.
    Merhige ME, Smalling RW, Cassidy D, Barrett R, Wise G, Short J, Wampler RK (1989) Effect of the Hemopump left ventricular assist device on regional myocardial perfusion and function: reduction of ischemia during coronary occlusion. Circulation 80(5)[Suppl III]:158–166Google Scholar
  10. 10.
    Magovern GJ, Park SB, Maher TD (1985) Use of a centrifugal pump without anticoagulants for postoperative left ventricular assist. World J Surg 9:25–36PubMedCrossRefGoogle Scholar
  11. 11.
    Bernstein EF, Dorman FD, Blackshear PL, Scott DR (1970) An efficient, compact blood pump for assisted circulation. Surgery 68(1):105–115PubMedGoogle Scholar
  12. 12.
    Golding LR, Jacobs G, Groves LK, Gill CC, Nose’ Y, Loop FD (1982) Clinical results of mechanical support of the failing left ventricle. J Thorac Cardiovasc Surg 83:597–601PubMedGoogle Scholar
  13. 13.
    Pae WE, Pierce WS, Pennock JL, Campbell DB, Waldhausen JA (1987) Long-term results of ventricular assist pumping in postcardiotomy cardiogenic shock. J Thorac Cardiovasc Surg 93:431–441Google Scholar
  14. 14.
    Pennington DG, Samuels LD, Williams G et al. (1985) Experience with the Pierce-Donachy ventricular assist device in postcardiotomy patients with cardiogenic shock. World J Surg 9:37–46PubMedCrossRefGoogle Scholar
  15. 15.
    Wampler RK, Moise JC, Frazier OH, Olsen DB (1988) In vivo evaluation of a peripheral vascular access axial flow blood pump. Trans Am Soc Artif Intern Organs 34(3):450–454Google Scholar
  16. 16.
    Wampler RK, Frazier OH, Lansing AM et al. (1991) Treatment of cardiogenic shock with the Hemopump left ventricular assist device. Ann Thorac Surg 52:506–513PubMedCrossRefGoogle Scholar
  17. 17.
    Johnson and Johnson Interventional Systems CD-0218 (1993) Final report-pending recovery of the natural heart, May 17 (IDE G870192/43)Google Scholar
  18. 18.
    Nimbus Medical (1990) Pre-market approval application hemopump - temporary cardiac assist system vols 1–4Google Scholar
  19. 19.
    Trapp WG, Bisarya R (1975) Placement of coronary artery bypass graft without pump oxygenator. Ann Thorac Surg 19:1–9PubMedCrossRefGoogle Scholar
  20. 20.
    Ankeney JL (1975) Coronary vein graft without cardiopulmonary bypass; a surgical motion picture. Ann Thorac Surg 1(19)Google Scholar
  21. 21.
    Buffolo E, Andrade JCS, Branco JNR, Aguiar LF, Ribeiro EE, Jatene AD (1990) Myocardial revascularization without extracorporeal circulation: seven-year experience in 593 cases. Eur J Cardiothorac Surg 4:504–508PubMedCrossRefGoogle Scholar
  22. 22.
    Benetti FJ, Naselli G, Wood M, Geffner L (1991) Direct myocardial revascularization without extracorporeal circulation. Chest 100(2):313–316CrossRefGoogle Scholar
  23. 23.
    Pfister AJ et al. (1992) Coronary artery bypass without cardiopulmonary bypass. Presented at the 28th Annual Meeting of the Society of Thoracic Surgeons, OrlandoGoogle Scholar
  24. 24.
    Glenville B, Ross D (1986) Coronary artery surgery with patient’s lungs as oxygenator. Lancet 333:1005–1006CrossRefGoogle Scholar
  25. 25.
    Sweeney MS, Frazier OH (1992) Device-supported myocardial revascularization: the benefits of avoiding pump oxygenation and cardiac arrest in operations upon dilapidated hearts. Presented at the 28th Annual Meeting of the Society of Thoracic Surgeons, OrlandoGoogle Scholar
  26. 26.
    Wampler R, Aboul-Hosn W, Cleary M, Saunders M (1993) The Sternotomy HEMOPUMP - a second-generation intraarterial ventricular assist device. ASAIO J 39(3):M218-M223PubMedCrossRefGoogle Scholar
  27. 27.
    Scholtz K, Figulla H, Schweda F, Smalling R, Heilige G, Kreuzer H, Aboul-Hosn W, Wampler R (1994) Mechanical left ventricular unloading during high-risk coronary angioplasty: first use of a new percutaneous transvalvular left ventricular assist device. Cathet Cardiovasc Diagn 31(61):61–69CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • W. Aboul-Hosn
  • R. Wampler

There are no affiliations available

Personalised recommendations