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Prinzipien der Strahlentherapie

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Kompendium Internistische Onkologie

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Zusammenfassung

Die zellulären, insbesondere molekularen Veränderungen, die nach Bestrahlung zum Tod der Zelle führen, sind nicht in allen Details geklärt. Als empfindlichstes Target für ionisierende Strahlen gilt die DNS. Nicht reparierte DNS-Läsionen wie Doppelstrangbrüche können sich zu chromosomalen Aberrationen entwickeln, die nach wenigen Zellzyklen den Verlust der Teilungsfähigkeit zur Folge haben. Die Zelle unterliegt dem sogenannten reproduktiven Zelltod.

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Authors
  1. M. Molls
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  2. W. Hoffmann
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  3. M. Bamberg
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  4. V. Budach
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  5. P. Fritz
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  6. M. Wannenmacher
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  7. W. Sauerwein
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  8. N. Willich
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  9. W. Rhomberg
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  10. R. Sauer
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  11. L. Keilholz
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Editor information

Editors and Affiliations

  1. Klinik für Hämatologie/Onkologie, Martin-Luther-Universitä Halle-Wittenberg, Ernst-Grube-Straße 40, 06120, Halle/Saale, Deutschland

    Hans-Joachim Schmoll

  2. Klinik und Poliklinik für Innere Medizin II, Klinikum der Friedrich-Schiller-Universität Jena, Erlanger Allee 101, 07740, Jena, Deutschland

    Klaus Höffken

  3. Medizinischen Klinik II Schwerpunkt Onkologie und Hämatologie, Humboldt-Universität, Universitätsklinikum Charité, Schumannstraße 20/21, 10117, Berlin, Deutschland

    Kurt Possinger (Direktor) (Direktor)

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Molls, M. et al. (1996). Prinzipien der Strahlentherapie. In: Schmoll, HJ., Höffken, K., Possinger, K. (eds) Kompendium Internistische Onkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79214-4_12

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