Endoscopy pp 106-108 | Cite as

Liver Biopsy: Modified Menghini and Trucut Needles for Fibrin Sealing of the Biopsy Channel: Clinical Experience

  • G. Judmaier
  • W. Vogel
  • H. P. Dinges
  • K. Zatloukal
Conference paper
Part of the Fibrin Sealing in Surgical and Nonsurgical Fields book series (ADMERE, volume 8)


Histologic investigation of liver tissue obtained by percutaneous needle biopsy remains the mainstay in the diagnosis of liver disease. Impaired blood clotting or thrombocytopenia precludes percutaneous liver biopsy for the danger of sometimes life-threatening hemorrhage as the most serious complication. The feasibility of plugging the intrahepatic needle track with fibrin sealant to minimize the risk of bleeding has been shown. The advantage of the method presented here is that biopsy and sealing can be performed as a one-step procedure, thus shortening the time necessary and minimizing the risk of complications. We considered laparoscopic control most reliable to optimize handling of the double-channel needles and to assess the reliability of fibrin plugging for the “blind” percutaneous approach. In 27 patients a modified Menghini needle and in 10 patients a modified Trucut needle were tested. In our experience the handling of the modified Trucut needle proved easier. There was, however, no significant difference in the length of the biopsy core obtained with the two needles (16 ± 8.6 mm Menghini needle and 15.75 ± 7.1 mm Trucut needle), resulting from the larger diameter of the Menghini needle (1.8). The thin trickle of bleeding observed around the plug in a few patients was without clinical significance, reflecting the prolonged coagulation time in these patients. In summary, in the hands of an experienced investigator the combined biopsy-plugging device is a safe and reliable tool for obtaining liver tissue in patients with impaired blood coagulation. As a one-step procedure it can be performed quickly, thus increasing safety by diminishing the need for patient cooperation.


Liver Biopsy Fibrin Sealant Percutaneous Approach Percutaneous Needle Biopsy Needle Track 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Lindner H (1967) Grenzen und Gefahren der perkutanen Leberbiopsie mit der Menghininadel. Dtsch med Wochenschr 92: 1751–1757PubMedCrossRefGoogle Scholar
  2. 2.
    Hegarty JE, Williams R (1984) Liver biopsy: techniques, clinical application and complication. Br Med J 288: 1254–1256CrossRefGoogle Scholar
  3. 3.
    Riley SA, Ellis WR, Irving HC, Lintott DJ, Axon ATR, Losowsky MS (1984) Percutaneous liver biopsy with plugging of needle track: a safe method for use in patients with impaired coagulation. Lancet ii: 436PubMedCrossRefGoogle Scholar
  4. 4.
    Chisholm RA, Jones SN, Lees WR (1989) Fibrin sealant as a plug for the post liver biopsy needle track. Clin Radiol 40: 627–628PubMedCrossRefGoogle Scholar
  5. Tobin MV, Gilmore IT (1989) Plugged liver biopsy in patients with impaired coagulation. Dig Dis Sci 34: 13–15PubMedCrossRefGoogle Scholar
  6. 6.
    Zatloukal K, Dinges HP, Thurnher M, Redl H, Schlag G (1988) A new technique of liver biopsy with plugging of the needle track using a double channel biopsy device. Z Gastroenterol 26: 699–703PubMedGoogle Scholar
  7. 7.
    Lebree D, Goldfarb G, Degott C, Rueff B, Benhamou J (1982) Transvenous liver biopsy. Gastroenterology 83: 338–340Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • G. Judmaier
  • W. Vogel
  • H. P. Dinges
  • K. Zatloukal

There are no affiliations available

Personalised recommendations