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Effects of Antibiotics on Endotoxin Release

  • Conference paper
Yearbook of Intensive Care and Emergency Medicine

Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 1995))

Abstract

Sepsis or septic shock is a serious life-threatening condition, which refers to a constellation of clinical signs, such as fever (or hypothermia), chills, organ dysfunction, hypotension or even shock, that suggest systemic infection. Recent evidence suggests that this clinical syndrome associated with gram-negative bacteremia (or serious local gram-negative infection) is most likely caused by endotoxin from the gram-negative bacterial cell wall. Although the endotoxin molecules can induce a clinical syndrome that is strikingly similar to septic shock, it has recently become clear that many of the features of septic shock result from a complex cascade of endogenous mediators triggered by the bacterial endotoxin.

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Authors
  1. A. S. M. Dofferhoff
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  2. J. Buys
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Editor information

Editors and Affiliations

  1. Department of Intensive Care, Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Clinical Director) (Clinical Director)

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© 1995 Springer-Verlag Berlin Heidelberg

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Dofferhoff, A.S.M., Buys, J. (1995). Effects of Antibiotics on Endotoxin Release. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine. Yearbook of Intensive Care and Emergency Medicine, vol 1995. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79154-3_38

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  • DOI: https://doi.org/10.1007/978-3-642-79154-3_38

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-58256-4

  • Online ISBN: 978-3-642-79154-3

  • eBook Packages: Springer Book Archive

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