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Oxidative Stress and Oxygen-Dependent Cytokine Production

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Book cover Yearbook of Intensive Care and Emergency Medicine

Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 1995))

Abstract

During critical illness, a complex hierarchy of inflammatory and cardiovascular changes is activated during the host response to diverse non-infectious and infectious stimuli. These produce stereotypic alterations in body temperature, heart rate, respiratory frequency, and circulating polymorphonuclear leukocytes (PMN), findings collectively termed the systemic inflammatory response syndrome (SIRS) [1]. Such expressions of inflammation during SIRS represent one end of a spectrum in which progressive derangements in the regulation of mediator production, PMN activation, endothelial function, and cardiovascular performance culminate in multiple organ failure (MOF) [2].

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Authors
  1. G. M. Matuschak
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Editor information

Editors and Affiliations

  1. Department of Intensive Care, Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Clinical Director) (Clinical Director)

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© 1995 Springer-Verlag Berlin Heidelberg

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Matuschak, G.M. (1995). Oxidative Stress and Oxygen-Dependent Cytokine Production. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine. Yearbook of Intensive Care and Emergency Medicine, vol 1995. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79154-3_33

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  • DOI: https://doi.org/10.1007/978-3-642-79154-3_33

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-58256-4

  • Online ISBN: 978-3-642-79154-3

  • eBook Packages: Springer Book Archive

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