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GM-CSF Modulates Immune Function and Improves Survival After Thermal Injury

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Abstract

As a result of major advances in the care of thermally injured patients over the last two decades, mortality from hypovolemic shock, acute renal failure, and metabolic wasting has fallen dramatically. However, infection remains an important cause of morbidity and mortality in these patients [1]. The prevalence and severity of septic episodes is largely secondary to profound alterations in defence mechanisms which often characterise the host’s response to major burn injury.

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References

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© 1995 Springer-Verlag Berlin Heidelberg

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Molloy, R.G., Holzheimer, R., Nestor, M., Collins, K., Mannick, J.R., Rodrick, M.L. (1995). GM-CSF Modulates Immune Function and Improves Survival After Thermal Injury. In: Engemann, R., Holzheimer, R., Thiede, A. (eds) Immunology and Its Impact on Infections in Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79079-9_34

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  • DOI: https://doi.org/10.1007/978-3-642-79079-9_34

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-58145-1

  • Online ISBN: 978-3-642-79079-9

  • eBook Packages: Springer Book Archive

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