Collagenase, Aid for Treatment of Decubitus Ulcers

  • M. W. F. van Leen
Conference paper


Despite optimal preventive measures it is Impossible to fully eliminate factors that could lead to a decubitus ulcer. In these wounds it is oten not possible to surgically remove the necrosis without damaging healthy tissue. In a multicenter study, 63 inpatients with decubitus ulcers grade III or IV were treated with collagenases once daily for 8 weeks; 60% of the patients had a clean wound after 2–4 weeks, The decrease of inflammatory symptoms was significant and alleviated the discomfort of the patients. This acceleration of the wound healing results in a quicker recovery of the patients and is therefore cost saving.


Granulation Tissue Healthy Tissue Decubitus Ulcer Wound Treatment Wound Size 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • M. W. F. van Leen
    • 1
  1. 1.Verpleeghuis de NaaldhorstMiddelbroekwegNaaldwijkNetherlands

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