Abstract
During the last decade strong evidence has been accumulated for a causal relationship between specific genetic alterations and the abnormal differentiation state and growth behaviour of malignant cells. Such alterations can be observed at different levels ranging from chromosome mutations to point mutations of certain genes and may arise in a given cell either spontaneously or due to the effect of mutagenic environmental factors.
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© 1994 Springer-Verlag Berlin Heidelberg
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Cremer, T. et al. (1994). Detection of Genetic Imbalances in Tumor Genomes by Fluorescence in situ Hybridization with Tumor Genomic DNA and Subregional DNA Probes. In: Obe, G., Natarajan, A.T. (eds) Chromosomal Alterations. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78887-1_5
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DOI: https://doi.org/10.1007/978-3-642-78887-1_5
Publisher Name: Springer, Berlin, Heidelberg
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