Skip to main content

Part of the book series: NATO ASI Series ((ASIH,volume 82))

  • 81 Accesses

Abstract

Although a great deal of effort has been directed towards understanding the mechanism of replication and segregation of chromosomes during cell division, not much is known about organelle segregation. Inheritance of organelles is an important concern to the cell, since de novo synthesis does not appear to be a commonly used mechanism. Some important questions are: (1) What regulatory molecules are responsible for initiating the process of organelle inheritance? (2) How is maternally derived material targeted to the daughter cell? (3) If vesiculation and fusion are involved, do these mechanisms use the same types of molecules involved in other cellular fusion events such as protein trafficking in the secretory pathway?

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Conradt, B., Shaw, J., Vida, T., Emr, S., and Wickner, W. (1992) In vitro reactions of vacuole inheritance in Saccharomyces cerevisiae. JCB 119:1469.

    Article  Google Scholar 

  • Gomez de Mesquita, D., Hoopen, R., and Woldringh, C. (1991) Vacuolar segregation to the bud of Sacchromyces cerevisae: an analysis of morphology and timing in the cell cycle. Journal of General Microbiology 137:2454.

    Google Scholar 

  • Preuss, D., Mulholland, C., Kaiser, C., Orlean, P., Albright, C., Rose, M., Robbins, P., and Botstein, D. (1991) Structure of the yeast endoplasmic reticulum: localization of ER proteins using immunofluorescence and immunoelectron microscopy. Yeast 7: 891.

    Article  PubMed  CAS  Google Scholar 

  • Redding, K., Holcomb, C., and Fuller, R. (1991) Immunolocalization of Kex2 protease identifies a putative late golgi compartment in the yeast Saccharomyces cerevisiae. JCB 113: 527.

    Article  PubMed  CAS  Google Scholar 

  • Shaw, J., and Wickner, W. (1991) vac-2: a yeast mutant which distinguishes vacuole segregation from golgi-to-vacuole protein targeting. EMBO 10:1741.

    CAS  Google Scholar 

  • Tuomikoski, T., Felix, M., Doree, M., and Gruenberg, J. (1989) Inhibition of endocytic vesicle fusion in vitro by the cell-cycle control protein kinase cdc2. Nature 342: 942.

    Article  PubMed  CAS  Google Scholar 

  • Warren, G. (1989) Mitosis and membranes. Nature 342: 857.

    Article  PubMed  CAS  Google Scholar 

  • Warren, G. (1985) Membrane traffic and organelle division. TIBS 10: 439.

    CAS  Google Scholar 

  • Warren, G., Featherstone, C., Griffiths, G., and Burke, B. (1983) Newly synthesized G protein of vesicular stomatitis virus is not transported to the cell surface during mitosis. JCB 97: 1623.

    Article  PubMed  CAS  Google Scholar 

  • Weisman, L., and Wickner, W. (1992) Molecular characterization of VAC1, a gene required for vacuole inheritance and vacuole protein sorting. JBC 267: 618.

    CAS  Google Scholar 

  • Weisman,L., Emr,S., and Wickner, W. (1990) Mutants of Saccharomyces cerevisiae that block intervacuole vesicular traffic and vacuole division and segregation. PNAS 87: 1076.

    Article  Google Scholar 

  • Weisman, L., and Wickner, W. (1988) Intervacuole exchange in the yeast zygote: a new pathway in organelle communication. Science 241: 589.

    Article  PubMed  CAS  Google Scholar 

  • Weisman, L., Bacallao, R., and Wickner, W. (1987) Multiple methods of visualizing the yeast vacuole permit evaluatin fo its morphology and inheritance during the cell cycle. JCB 105: 1539.

    Article  PubMed  CAS  Google Scholar 

  • Yaffe, M. (1992) Organelle inheritance in the yeast cell cycle. TICB, in press.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Nicolson, T., Wickner, W. (1994). Organelle Inheritance in Budding Yeast. In: Op den Kamp, J.A.F. (eds) Biological Membranes: Structure, Biogenesis and Dynamics. NATO ASI Series, vol 82. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78846-8_30

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-78846-8_30

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-78848-2

  • Online ISBN: 978-3-642-78846-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics