HLA.DQ-Alpha and D1S80 Data from a French Caucasian Population Random Sample Versus a Sample of Aircrash Victims
On January 20, 1992, an airbus A320 crashed in Strasbourg area: among the 90 passengers and the 6 crew, 87 died and 9 survived. Identification of the victims was investigated using conventional methods (dental records, physical and X rays examinations) and DNA fingerprinting. Then, the complete reconstitution of most heavy mutilated bodies was performed by DNA typing at the HLA.DQ-Alpha (1) and D1S80 (2) loci for all the human fragments. The HLA.DQ-Alpha and D1S80 data collected for 84 and 85 victims respectively were compared to the data obtained for a sample of individuals taken at random from the french caucasian population. Allele and genotype frequencies at the HLA.DQ-Alpha and D1S80 loci were determined by polymerase chain reaction (PCR) amplification.
KeywordsVNTR Locus Specific Oligonucleotide Probe Dental Record Sequence Specific Oligonucleotide Probe Human Fragment
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- 2).Budowle B, Chakraborty R, Giusti A, Eisenberg AJ and Allen RC (1990) Analysis of the VNTR locus D1S80 by the PCR followed by high-resolution PAGE. Am J Hum Genet 48: 137–144.Google Scholar
- 3).Helmuth R, Fildes N, Blake E, Luce MC, Chimera J, Madij R, Gorodezky C, Stoneking M, Schmill N, Klitz W, Higuchi R and Erlich HA (1990) HLA.DQ-Alpha allele and genotype frequencies in various human populations, determined by using enzymatic amplification and oligonucleotide probes. Am J Hum Genet 47: 515–523.PubMedGoogle Scholar