Histomorphological Characteristics of Metastases of Soft Tissue Sarcomas
Patients with malignant soft tissue tumors may exhibit metastatic disease at the time of first diagnosis, but this a rare event. More often, metastases develop during the course of the disease, either via the blood stream or through the lymphatics. Once metastases have occurred, the prognosis becomes very poor despite the availability of multimodality treatment with surgery, radiation, and chemotherapy. The probability of metastatic spread is determined by several factors. Among these are tumor site, tumor size, histological subtype, grade, and type of therapy.
KeywordsSoft Tissue Sarcoma Synovial Sarcoma Malignant Fibrous Histiocytoma Regional Lymph Node Metastasis Epithelioid Sarcoma
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