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Mechanismen der Sekretion des exokrinen Pankreas

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Ökosystem Darm V

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Zusammenfassung

Die exokrine Zelle des Pankreas ist ein Modellfall für Zellen mit hoher Eiweißsynthese und Sekretion. Durch ihre polare Struktur mit einem basolateralen und einem luminalen Anteil eignet sie sich ideal zur Erforschung grundlegender Sekretionsmechanismen. Diese Einschätzung stammt von George Palade, der für die Klärung der intrazellulären Transport- und Sekretionsmechanismen den Nobel-Preis verliehen bekam [1]. Im folgenden sollen die einzelnen Transportschritte in der Azinus-zelle von der Synthese bis zur Exozytose erläutert werden. Daneben werden die hierfür erforderlichen Schritte der Signaltransduktion zusammengefaßt.

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Authors
  1. M. M. Lerch
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  2. G. Adler
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Editor information

Editors and Affiliations

  1. Innere Medizin II, Medizinische Klinik und Poliklinik, Universitätskliniken des Saarlandes, 66421, Homburg/Saar, Deutschland

    Martin Zeitz

  2. Zentrum der Inneren Medizin, Universitätsklinikum, Theodor-Stem-Kai 7, 60596, Frankfurt, Deutschland

    W. F. Caspary

  3. Nationales Referenzzentrum für Enteritiserreger, Hygienisches Institut, Marckmannstraße 129a, 20539, Hamburg, Deutschland

    Jochen Bockemühl

  4. Medizinsche Klinik, Städtisches Krankenhaus Solingen, Postfach, 42719, Solingen, Deutschland

    Gerd Lux

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© 1993 Springer-Verlag Berlin Heidelberg

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Lerch, M.M., Adler, G. (1993). Mechanismen der Sekretion des exokrinen Pankreas. In: Zeitz, M., Caspary, W.F., Bockemühl, J., Lux, G. (eds) Ökosystem Darm V. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78733-1_5

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  • DOI: https://doi.org/10.1007/978-3-642-78733-1_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-57591-7

  • Online ISBN: 978-3-642-78733-1

  • eBook Packages: Springer Book Archive

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