Function of Molecular Chaperones in Protein Folding
How a newly synthesized polypeptide chain acquires its specific three-dimensional structure is a fundamental problem in biology. Only in recent years, however, have cell biologists and physical biochemists turned their attention to the process of protein folding as it occurs in vivo. As a result, the long-held view that proteins in the cell fold in a largely spontaneous process has been called into question.
KeywordsMolecular Chaperone Ribulose Bisphosphate Folding Intermediate Protein DnaJ Nascent Polypeptide Chain
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