Abstract
Nearly all human renal cell carcinomas (RCC) are found to be encapsuled [3], Histological assessment using conventional staining techniques such as hematoxylin and eosin (H&E) reveals a capsule surrounding the tumor which might act as a barrier between normal and malignant tissue. However, the exact origin and function of this capsule is unknown. In 1925 Lubarsch was the first to describe renal tumors exhibiting tumor capsules [7]. He called this tissue structure a pseudocapsule. Up to now investigations concerning this tissue phenomenon have been very rare.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Cordell JL, Falini B, Erber NW, Ghosh AK, Abdulaziz Z, Mac-Donald S, Pulford KAF, Stein H, Mason DY (1984) Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal antialkaline phosphatase (APAAP complexes). J Histochem Cytochem 32: 219–229
Karnovsky MJ (1971) Use of ferrocyanide-reduced osmium tetroxide in electron microscopy. Abstracts of the American Society of Cell Biology, New Orleans, p 146
de Kernion JB (1986) Renal tumors. In: Walsh PC, Gittes RF, Perlmutter AD, Stamey TA (eds) Campbell’s urology, vol 2. Saunders, Philadelphia, pp 1297–1342
Kirchner H, de Riese W, Allhoff E, Poliwoda H, Atzpodien J (1991) Immunotherapy of advanced renal cell cancer using subcutaneous recombinant interleukin-2 and interferon-alpha. World J Urol 9: 219–222
Kuehn K, Panzer J, Luciano L, Reale E (1985) Identification of proteoglycans in the rat and human glomerular basement membrane. In: Lubec G, Hudson BG (eds) Glomerular basement membrane. Libbey, London, pp 17–20
Lelle RJ, Heidenreich W, Stauch G, Gerdes J (1987) The correlation of growth fractions with histologic grading and lymph node status in human mammary carcinoma. Cancer 59: 83–88
Lubarsch O (1925) Die destruierenden Nierengewaechse. In: Henke F, Lubarsch O (eds) Handbuch der speziellen pathologischen Anatomie und Histologie. Springer, Berlin, p 636
de Riese W, Allhoff EP (1991) Einsatz von Biological Response Modifiers in der Behandlung des metastasierten Nierenzellkarzinoms; Review der klinischen Daten. In: de Riese W, Allhoff EP, Schuth J, Jonas U (eds) Das metastasierte Nierenzellkarzinom, Klinik und therapeutische Aspekte. Springer, Berlin Heidelberg New York, pp 25–41
de Riese W, Reale E (1991) The capsule of the renal cell carcinoma contains modified smooth muscle cells. J Submicrosc Cytol Pathol 23(2): 237–244
de Riese W, Allhoff E, Werner M, Atzpodien J, Kirchner H, Stief CG, Djamilian M, Schlick R, Jonas U (1991) Proliferative behaviour and cytogenetic changes in human renal cell carcinoma (RCC). World J Urol 9: 79–85
Yagoda A (1992) Cytotoxic chemotherapy trials between 1983 and 1990 for advanced renal cell carcinoma. In: Staehler G, Pomer S (eds) Basic and clinical research on renal cell carcinoma. Springer, Berlin Heidelberg New York, pp 71–78
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1994 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
de Riese, W. et al. (1994). Investigation of the Tumor Capsule in Renal Cell Carcinoma and Its Significance for Treatment. In: Staehler, G., Pomer, S. (eds) Contemporary Research on Renal Cell Carcinoma. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78609-9_6
Download citation
DOI: https://doi.org/10.1007/978-3-642-78609-9_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-78611-2
Online ISBN: 978-3-642-78609-9
eBook Packages: Springer Book Archive