Toxoplasmosis pp 109-121 | Cite as

Recent Advances in the Glycobiology of Toxoplasma Gondii

  • Ralph T. Schwarz
  • Stanislas Tomavo
  • Maria Odenthal-Schnittler
  • Boris Striepen
  • Dirk Becker
  • Martina Eppinger
  • Christina F. Zinecker
  • Jean François Dubremetz
Conference paper
Part of the NATO ASI Series book series (volume 78)


Posttranslational modifications of proteins by oligossaccharides and glycolipids play an important role for the structure, biosynthesis and biological function of surface membrane proteins of viruses, bacteria and eukaryotic cells including parasitic protozoa. Until recently very little on the glycobiology of Toxoplasma gondii was known and considerable controversy as to the presence of glycoproteins as major surface components of the Toxoplasma existed [Handman et al., 1980; Johnson et al., 1981; Mauras et aL, 1980; Naot et al., 1983; Sharma et al., 1983]. It has now become apparent that the major membrane surface proteins of T. gondii are modified by glycoconjugates. Their role in the biology and pathology of the parasite remains to be elucidated in detail.


Toxoplasma Gondii Trypanosoma Brucei Membrane Anchor Mannose Residue Variant Surface Glycoprotein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • Ralph T. Schwarz
    • 1
  • Stanislas Tomavo
    • 1
    • 2
  • Maria Odenthal-Schnittler
    • 1
  • Boris Striepen
    • 1
  • Dirk Becker
    • 1
  • Martina Eppinger
  • Christina F. Zinecker
    • 1
  • Jean François Dubremetz
    • 1
    • 3
  1. 1.Zentrum für Hygiene und Medizinische MikrobiologiePhilipps-Universität MarburgMarburgGermany
  2. 2.Dept. of Microbiology and ImmunologyStanford Univ. School of MedicineStanfordUSA
  3. 3.Unité 42 de l’INSERMVilleneuve d’AscqFrance

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