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The Pharmacology of Alcohol Abuse pp 121–137Cite as

Involvement of CNS Catecholamines in Alcohol Self-Administration, Tolerance and Dependence: Preclinical Studies

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 114))

Abstract

The role of the CNS catecholamines dopamine (DA) and norepinephrine (NE) has been studied for many years in relation to ethanol’s actions. This is partially because these two neurotransmitters have been intensively studied in the field of neuroscience. A complete review of all of the studies carried out over the last 25 years is beyond the scope and limitations of this chapter. For an overview of earlier work, the reader is referred to prior reviews (HOFFMAN and TABAKOFF 1985; HUNT 1990; POHORECKY and BRICK 1988; TABAKOFF and HOFFMAN 1991).

Some portions of this chapter have appeared previously in the referenced reviews.

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Authors
  1. H. H. Samson
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  2. P. L. Hoffman
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  1. Division of Addictive Disorders, Department of Psychiatry, MC2103, University of Connecticut School of Medicine, 263 Farmington Avenue, 06030, Farmington, CT, USA

    Henry R. Kranzler M.D. (Associate Professor and Director) (Associate Professor and Director)

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Samson, H.H., Hoffman, P.L. (1995). Involvement of CNS Catecholamines in Alcohol Self-Administration, Tolerance and Dependence: Preclinical Studies. In: Kranzler, H.R. (eds) The Pharmacology of Alcohol Abuse. Handbook of Experimental Pharmacology, vol 114. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78435-4_6

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