Elevated Plasma Neuropeptide Y as a Marker of B Cell Precursor Leukemia in Children
Neuropeptida Y (NPY) was investigated in childhood acute leukemia using a competitive radioimmunoassay, northern Blot and in situ hybridization. Plasma NPY was mainly elevated in children with leukemia with favourable outcome and may be used as a marker of B cell precursor ALL (sensitivity 80%, specificity 100%). NPY mRNA was detected in leukemic bone narrow in CD10+ lymphoblasts.
KeywordsZinc Migration Leukemia Polypeptide Neuroblastoma
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