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Modulation of Maxi-Calcium-Activated K Channels: Role of Ligands, Phosphorylation, and G-Proteins

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GTPases in Biology II

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 108 / 2))

Abstract

Calcium-activated K channels are present in a vast number of tissues, including: brain, skeletal and smooth muscles, epithelia, and secretory glands. They have been classified in terms of their conductance as “maxi” (BK; ≈150-300pS), “intermediate” (IK; ≈100pS), and “small” (SK; <100pS) Ca-activated K (KCa) channels (for review see Latorre et al. 1989; Cook and Young 1990; McManus 1991).

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Authors
  1. L. Toro
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  2. E. Stefani
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Editors and Affiliations

  1. Baylor College of Medicine, Department of Medicine Cell Biology and Experimental Therapeutics, Houston VA Medical Center, Room 3C-385, 2002 Holcombe Boulevard, Houston, TX, 77030, USA

    Burton F. Dickey M.D.

  2. Department of Cell Biology, Molecular Physiology and Biophysics, Medicine and Neurosciences, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA

    Lutz Birnbaumer Ph.D.

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© 1993 Springer-Verlag Berlin Heidelberg

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Toro, L., Stefani, E. (1993). Modulation of Maxi-Calcium-Activated K Channels: Role of Ligands, Phosphorylation, and G-Proteins. In: Dickey, B.F., Birnbaumer, L. (eds) GTPases in Biology II. Handbook of Experimental Pharmacology, vol 108 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78345-6_35

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  • DOI: https://doi.org/10.1007/978-3-642-78345-6_35

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-78347-0

  • Online ISBN: 978-3-642-78345-6

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