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Adhesion in Leukocyte Homing and Differentiation pp 109–124Cite as

Migration of Activated Lymphocytes

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 184))

Abstract

When lymphocytes leave the primary lymphoid organs as mature but naive cells, they enter the recirculating pool, moving continuously from the blood into the secondary lymphoid organs, spleen, lymph nodes and Peyer’s patches, from which they return, directly or via efferent lymph, back to the blood (Gowans and Knight 1964). In addition, some of the cells also pass through nonlymphoid tissues, such as lung, liver, gut wall or skin, from which they return into circulation either directly or via afferent lymph/lymph nodes/efferent lymph (Fig. 1).

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  1. Department of Immunology, Medical Clinic, Universitätskrankenhaus Eppendorf, 20246, Hamburg, Germany

    A. Hamann & S. Rebstock

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  1. A. Hamann
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  1. Basel Institute for Immunology, Grenzacherstr. 487, 4005, Basel, Switzerland

    Dominique Dunon Ph.D. , Charles R. Mackay Ph.D.  & Beat A. Imhof Ph.D. ,  & 

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Hamann, A., Rebstock, S. (1993). Migration of Activated Lymphocytes. In: Dunon, D., Mackay, C.R., Imhof, B.A. (eds) Adhesion in Leukocyte Homing and Differentiation. Current Topics in Microbiology and Immunology, vol 184. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78253-4_9

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