Migration of Activated Lymphocytes

  • A. Hamann
  • S. Rebstock
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 184)


When lymphocytes leave the primary lymphoid organs as mature but naive cells, they enter the recirculating pool, moving continuously from the blood into the secondary lymphoid organs, spleen, lymph nodes and Peyer’s patches, from which they return, directly or via efferent lymph, back to the blood (Gowans and Knight 1964). In addition, some of the cells also pass through nonlymphoid tissues, such as lung, liver, gut wall or skin, from which they return into circulation either directly or via afferent lymph/lymph nodes/efferent lymph (Fig. 1).


High Endothelial Venule Lymphocyte Migration Homing Receptor Lymphocyte Homing Afferent Lymph 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1993

Authors and Affiliations

  • A. Hamann
    • 1
  • S. Rebstock
    • 1
  1. 1.Department of Immunology, Medical ClinicUniversitätskrankenhaus EppendorfGermany

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