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Neuronal Protection: Is There a Role for Gangliosides or Ca+2-Channel Blockers?

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Thrombolytic Therapy in Acute Ischemic Stroke II

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Abstract

Recently developed experimental data, and initial clinical data for ischemic stroke suggest that the sooner therapeutical intervention in ischemic stroke may achieve recanalization, the better the outcome. TIAs are a natural example of this statement, and a model for an effective and safe thrombolytic therapy. The GISSI studies have underlined the validity of this concept for cardiac ischemia [1, 11]. However, for the ischemic brain, reperfusion does not appear to be without side effects [5, 7, 20], which may be not unimportant for a patient’s very survival and final clinical outcome.

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Author information

Authors and Affiliations

  1. Department of Neurological Sciences, University of Rome, Rome, Italy

    G.-L. Lenzi

  2. PH-SM, Funzione Medica, Bayer Spa, Milano, Italy

    H. Baasch

  3. Fidia Spa, Abano Terme, Padova, Italy

    R. Bruno

Authors
  1. G.-L. Lenzi
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  2. H. Baasch
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  3. R. Bruno
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Editor information

Editors and Affiliations

  1. Department of Molecular and Experimental Medicine, The Scripps Research Institute and Division of Hematology/Medical Oncology, Scripps Clinic and Research Foundation, 10666 North Torrey Pines Road, La Jolla, CA, 92037, USA

    Gregory J. del Zoppo M.D.

  2. Neurology Service, Hyogo Brain and Heart Center at Himeji, 520 Saisho-ko, Himeji, 670, Japan

    Etsuro Mori M.D.

  3. Neurologische Klinik, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 400, W-6900, Heidelberg 1, Germany

    Werner Hacke

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© 1993 Springer-Verlag Berlin Heidelberg

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Lenzi, GL., Baasch, H., Bruno, R. (1993). Neuronal Protection: Is There a Role for Gangliosides or Ca+2-Channel Blockers?. In: del Zoppo, G.J., Mori, E., Hacke, W. (eds) Thrombolytic Therapy in Acute Ischemic Stroke II. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78061-5_37

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  • DOI: https://doi.org/10.1007/978-3-642-78061-5_37

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-56442-3

  • Online ISBN: 978-3-642-78061-5

  • eBook Packages: Springer Book Archive

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