Spectacular Shrinking Deficits in Acute Ischemic Stroke

  • K. Minematsu


The development of ischemic brain injury depends upon the severity and duration of ischemia [9, 13]. Compromised brain tissues may recover if blood flow is restored after a brief duration of ischemia [4, 13, 14, 17, 24, 27]. This concept has led to therapeutic attempts to restore flow in animal stroke models, and in human stroke, with thrombolytic therapy [3, 6, 29]. Successful salvage of brain tissues will likely require intervention within a few hours after interruption of the cerebral blood supply. During this time-window, however, acute ischemic stroke patients often recover spontaneously from the initial deficits


Middle Cerebral Artery Acute Ischemic Stroke Thrombolytic Therapy Stroke Onset Hemorrhagic Transformation 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • K. Minematsu
    • 1
  1. 1.National Cardiovascular Center Research InstituteOsakaJapan

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