Advertisement

Phylogenetic and Conceptual Aspects of the Subcommissural Organ

  • A. Oksche

Abstract

The subcommissural organ (SCO) is a unique secretory structure of the vertebrate brain. It consists of specialized ependymal and ependymal-derived cells of neuroepithelial origin — elements of glial lineage. Because of its extensive secretory activity and the chemical properties of its secretion, this array of cells assumes, among plain ependymal and glial elements, a position similar to that of neurosecretory nerve cells among ordinary neurons. Incontrast to the extended apparatus of neuroendocrine, especially peptidergic neurons, the phenomenon of ependyma- or glia-related secretion (see Knowles 1969) appears to be restricted to a few specialized formations. In a number of ependymal complexes, formerly claimed to be secretory (see Studnička 1900; Legait 1942), the elements possessing a secretory capacity are actually closely adjacent neurons (see Oksche 1969). Furthermore, granular inclusions of glial cells supposed to indicate an extended interstitial gland of the brain (as suggested by Nageotte 1910) were more recently proven to be regular cell organelles.

Keywords

Posterior Commissure Pineal Organ Secretory Material Circumventricular Organ Conceptual Aspect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Adam H (1957) Beitrag zur Kenntnis der Hirn Ventrikel und des Ependyms bei den Cyclostomen. Anat Anz 103: 173–188Google Scholar
  2. Adam H (1963) Brain ventricles, ependyma and related structures. In: Brodai A, Fänge R (eds) The biology of Myxine. Universitetsforlaget, Oslo, pp 137–149Google Scholar
  3. Bargmann W (1949) Über die neurosekretorische Verknüpfung von Hypothalamus und Neurohypophyse. Z Zellforsch 34: 610–634PubMedGoogle Scholar
  4. Chouaf L, Didier-Bazes M, Hardin H, Aguera M, Fevre-Montange M, Voutsinos B, Belin MF (1991) Developmental expression of glial markers in ependymocytes of the rat subcommissural organ: role of the environment. Cell Tissue Res 266: 553–561PubMedCrossRefGoogle Scholar
  5. Diederen JHB (1972) Influence of light and darkness on the subcommissural organ of Rana temporaria L. A cytological and autoradiographical study. Z Zellforsch 129: 237–255PubMedCrossRefGoogle Scholar
  6. Diepen R (1962) Der Hypothalamus. In: Bargmann W (ed) Handbuch der mikroskopischen Anatomie des Menschen, vol 4, part 7. Springer, Berlin Göttingen HeidelbergGoogle Scholar
  7. Galeotti G (1897) Studio morphologico e citologico della volta del diencefalo in alcuni vertebrati. Riv Pat Nerv 2: 481–517Google Scholar
  8. Herrera H, Rodríguez EM (1990) Secretory glycoproteins of the rat subcommissural organ are N-linked complex-type glycoproteins. Demonstration by combined use of lectins and specific glycosidases, and by the administration of Tunicamycin. Histochemistry 93: 607–615PubMedCrossRefGoogle Scholar
  9. Hofer H (1959) Zur Morphologie der circumventriculären Organe des Zwischenhirns der Säugetiere. Verh Dtsch Zopi Ges Frankfurt 1958, Zool Anz 22: 202–251Google Scholar
  10. Hofer H, Merker G, Oksche A (1976) Atypische Formen des Pinealorgans der Säugetiere. Anat Anz 140 [Suppl]: 97–102Google Scholar
  11. Legait E (1942) Les organes épendymaires du troisième ventricle. L’organe souscommissural. L’organe sub-foraical. L’organe para-ventriculaire. Med Thesis, University of NancyGoogle Scholar
  12. Meiniel R, Meiniel A (1985) Analysis of the secretions of the subcommissural organ of several vertebrate species by use of fluorescent lectins. Cell Tissue Res 239: 359–364PubMedCrossRefGoogle Scholar
  13. Meiniel R, Duchier-Liris N, Molat J-L, Meiniel A (1991) The complex-type glycoprotein secreted by the bovine subcommissural organ: an immunological study using C1 B8 A8 monoclonal antibody. Cell Tissue Res 266: 483–490PubMedCrossRefGoogle Scholar
  14. Nageotte J (1910) Phénomènes de sécrétion dans le protoplasma des cellules névrogliques de la substance grise. C R Soc Biol (Paris) 68: 1068–1069Google Scholar
  15. Oksche A (1954) Über die Art und Bedeutung sekretorischer Zelltätigkeit in der Zirbel und im Subcommissuralorgan. Anat Anz 101 [Suppl]: 88–96Google Scholar
  16. Oksche A (1956) Funktionelle histologische Untersuchungen über die Organe des Zwischenhirndaches der Chordaten. Anat Anz 102: 204–419Google Scholar
  17. Oksche A (1961) Vergleichende Untersuchungen über die sekretorische Aktivität des Subcommissuralorgans und den Gliacharakter seiner Zellen. Z Zellforsch 54: 549–612PubMedCrossRefGoogle Scholar
  18. Olsson R (1955) Structure and development of Reissner’s fibre in the caudal end of Amphioxus and some lower vertebrates. Acta Zool (Stockh) 36: 167–198CrossRefGoogle Scholar
  19. Olsson R (1956) The development of Reissner’s fibre in the brain of the salmon. Acta Zool (Stockh) 37: 235–250CrossRefGoogle Scholar
  20. Olsson R (1958a) Studies on the subcommissural organ. Acta Zool (Stockh) 39: 71–102CrossRefGoogle Scholar
  21. Olsson R (1958b) The subcommissural organ. Handström, StockholmGoogle Scholar
  22. Reissner E (1860) Beiträge zur Kenntnis vom Bau des Rückenmarks von Petromyzon fluviatilis L. Arch Anat Physiol 1960: 545–588Google Scholar
  23. Rodríguez EM, Oksche A, Hein S, Rodríguez S, Yulis R (1984) Comparative immunocytochemical study of the subcommissural organ. Cell Tissue Res 237: 427–441PubMedGoogle Scholar
  24. Rodríguez EM, Herrera H, Peruzzo B, Rodríguez S, Hein S, Oksche A (1986) Light- and electron-microscopic immunocytochemistry and lectin histochemistry of the subcommissural organ. Evidence for processing of the secretory material. Cell Tissue Res 243: 545–559PubMedCrossRefGoogle Scholar
  25. Rodríguez EM, Hein S, Rodríguez S, Herrera H, Peruzzo B, Nualart F, Oksche A (1987a) Analysis of the secretory products of the subcommissural organ. In: Scharrer B, Korf HW, Hartwig HG (eds) Functional morphology of neuroendocrine systems. Springer, Berlin Heidelberg New York, pp 189–202Google Scholar
  26. Rodríguez EM, Oksche A, Rodríguez S, Hein S, Peruzzo B, Schoebitz K, Herrera H (1987b) The subcommissural organ. In: Gross EM (ed) Circumventricular organs and body fluids, vol II. CRC Press, Boca Raton, pp 1–41Google Scholar
  27. Rodríguez S, Rodriguez EM, Jara P, Peruzzo B, Oksche A (1990) Single injection into the cerebrospinal fluid of antibodies against the secretory material of the subcommissural organ reversibly blocks formation of Reissner’s fiber: immunocytochemical investigations in the rat. Exp Brain Res 81: 113–124PubMedCrossRefGoogle Scholar
  28. Sterba G (1962) Das Subcommissuralorgan von Lampetra planeri (Bloch). Zool Jahrb Anat 80: 135–158Google Scholar
  29. Sterba G (ed) (1969) Zirkumventrikuläre Organe und Liquor. Fischer, JenaGoogle Scholar
  30. Sterba G (1972) Subcommissuralorgan und Liquorregulation. Biol Rundschau 10: 309–324Google Scholar
  31. Sterba G, Bargmann W (eds) (1977) Circumventriculäre Organe. Nova Acta Leopoldina, Suppl 9. Deutsche Akademie der Naturforscher, HalleGoogle Scholar
  32. Sterba G, Müller H, Naumann (1967) Fluoreszenz- und elektronenmikroskopische Untersuchungen über die Bildung des Reissnerschen Fadens bei Lampetra planeri (Bloch). Z Zellforsch 76: 355–376PubMedCrossRefGoogle Scholar
  33. Sterba G, Kleim I, Naumann W, Petter H (1981) Immunocytochemical investigation of the subcommissural organ in the rat. Cell Tissue Res 218: 659–662PubMedCrossRefGoogle Scholar
  34. Sterba G, Kiessig C, Naumann W, Petter H, Kleim I (1982) The secretion of the subcommissural organ. A comparative immuncytochemical investigation. Cell Tissue Res 226: 427–439PubMedCrossRefGoogle Scholar
  35. Studnička FK (1900) Untersuchungen über den Bau des Ependyms der nervösen Centralorgane. Anat, Hefte Wiesbaden 15: 303–430Google Scholar
  36. Stutinsky F (1950) Colloïde, corps de Herring et substance Gomori positive de la neurohypophse. C R Soc Biol (Paris) 144: 1357–1360Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • A. Oksche

There are no affiliations available

Personalised recommendations