Lectins as Indicators of Disease-Associated Glycoforms

  • N. Sumar
  • K. B. Bodman
  • P. M. Rudd
Part of the Springer Laboratory book series (SLM)

Abstract

Alterations in protein glycosylation are associated with many diseases; these may be useful markers of a disease state, reflecting changes in the environment in which proteins are glycosylated. Both the carbohydrate structure and the concentration of glycoproteins may change in disease, providing diagnostic information. Examples of glycoproteins where such modifications have been described include the tumor products alpha-fetoprotein (AFP), chorionic gonadotropin (HCG), and alpha antitrypsin and the plasma proteins IgG, transferrin, α-1 acid glycoprotein, and fibrinogen.

Keywords

Sugar Carbohydrate Fibrinogen Biotin Auger 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • N. Sumar
  • K. B. Bodman
  • P. M. Rudd

There are no affiliations available

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