The Effect of Hypoxia on Intracranial Pressure and Cerebral Blood Flow
The cerebrovascular response to oxygen has been well described previously by McDowall and others [3, 5]. These studies were primarily directed towards observing changes in cerebral blood flow (CBF), rather than intracranial pressure (ICP). ICP was often not recorded, or if it was, a fluid filled catheter or cisternal needle and external transducer were used. In view of advances in ICP methodology in the form of catheter tip transducers, we decided to reinvestigate the ICP and CBF responses to hypoxia using this technique. We were also interested in the relationship between ICP and CBF.
KeywordsCerebral Blood Flow Cerebral Blood Flow Change Cerebral Blood Flow Measurement Cerebral Blood Flow Response Cerebrovascular Response
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Aukland K, Bower FB, Berliner RW (1964) Measurement of local blood flow with hydrogen gas. Circ Res 14:164–187PubMedGoogle Scholar
Iragui-Madoz VJ, Wiederholt WC (1977) Far-field somatosensory evoked potentials in the cat. Electroencephalogr Clin Neurophysiol 43:646–657PubMedCrossRefGoogle Scholar
Jones MD, Traystman RJ, Simmons MA, Molten RA (1981) Effects of changes in arterial O2
content on cerebral blood flow in the lamb. Am J Physiol 240:H209–215PubMedGoogle Scholar
Krasney JA, Jensen JB, Lassen NA (1990) Cerebral Blood Flow Does Not Adapt to Sustained Hypoxia. J Cereb Blood Flow Metab 10:759–764PubMedCrossRefGoogle Scholar
McDowall DG (1966) Interrelationships between blood oxygen tensions and cerebral blood flow. In: Payne JP, Hill DW (eds) A Symposium on Oxygen measurements in Blood and Tissues. Churchill, London, pp 205–219Google Scholar
Milde LN, Milde JH, Gallagher WJ (1989) Cerebral effects of fentanyl in dogs. Brit J Anaesth 63:710–715PubMedCrossRefGoogle Scholar
Miller JD (1985) Head Injury And Brain Ischaemia- Implications For Therapy. Brit J Anaesth 57:120–130PubMedCrossRefGoogle Scholar
Ostrup RC, Luerssen TG, Marshall LF, Zornow MH (1987) Continuous monitoring of intracranial pressure with a minaturized fiberoptic device. J Neurosurg 67:206–209PubMedCrossRefGoogle Scholar
Sebel PS, Bovil JG, Van Der Haven A (1982) Cardiovascular effects of alfentanil anaesthesia. Brit J Anaesth 54:1185–1189PubMedCrossRefGoogle Scholar
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