The Effect of Hypoxia on Intracranial Pressure and Cerebral Blood Flow

  • J. B. North
  • P. L. Reilly
  • D. Gorman
  • C. Grant
  • G. L. Ludbrook


The cerebrovascular response to oxygen has been well described previously by McDowall and others [3, 5]. These studies were primarily directed towards observing changes in cerebral blood flow (CBF), rather than intracranial pressure (ICP). ICP was often not recorded, or if it was, a fluid filled catheter or cisternal needle and external transducer were used. In view of advances in ICP methodology in the form of catheter tip transducers, we decided to reinvestigate the ICP and CBF responses to hypoxia using this technique. We were also interested in the relationship between ICP and CBF.


Cerebral Blood Flow Cerebral Blood Flow Change Cerebral Blood Flow Measurement Cerebral Blood Flow Response Cerebrovascular Response 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • J. B. North
    • 1
  • P. L. Reilly
    • 1
  • D. Gorman
    • 2
  • C. Grant
    • 1
  • G. L. Ludbrook
    • 3
  1. 1.Departments of NeurosurgeryRoyal Adelaide HospitalAdelaideAustralia
  2. 2.Royal New Zealand Naval HospitalAucklandNew Zealand
  3. 3.AnaesthesiaRoyal Adelaide HospitalAdelaideAustralia

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