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Amino-Acids Release in Cerebrospinal Fluid After Injury of Cat Brain with Cold Lesion

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Abstract

Excessive concentration of some amino-acids have recently been found to injure neurons in the central nervous system [2]. Similar injuries to the nervous system seem to occur in patients with head injury due to excessive release of amino-acids from the lesion in the brain into the extracellular space or the cerebrospinal fluid (CSF) space. We investigated the relationship between changes in electrical activity and in concentrations of amino-acids in the CSF during edema formation after a brain contusion. We constructed a model of a cat brain with a cold injury to clarify the relationship.

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References

  1. Kuchiwaki H, Inao S, Nagasaka M, Andoh K, Hirano T, Sugita K (1990) The effects of cerebral hemodynamics on the progression of cold-induced oedema. Acta Neurochirurgica, Suppl 51:77–78

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  2. Olney JW, de Gubareff T, Labruyere J (1983) Seizure-related brain damage induced by cholinergic agents. Nature 301:520–522

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© 1993 Springer-Verlag Berlin Heidelberg

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Kuchiwaki, H., Inao, S., Kanaiwa, H., Hirano, T., Sugita, K. (1993). Amino-Acids Release in Cerebrospinal Fluid After Injury of Cat Brain with Cold Lesion. In: Avezaat, C.J.J., van Eijndhoven, J.H.M., Maas, A.I.R., Tans, J.T.J. (eds) Intracranial Pressure VIII. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77789-9_26

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  • DOI: https://doi.org/10.1007/978-3-642-77789-9_26

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77791-2

  • Online ISBN: 978-3-642-77789-9

  • eBook Packages: Springer Book Archive

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