Comparison of Sodium Nitroprusside and Labetalol on the Intracranial Pressure of Cats

  • S. Thiagarajah
  • E. Lear
  • I. Azar
Conference paper

Abstract

The commonly used antihypertensive agent sodium nitroprusside (SNP) increases intracranial pressure and causes tachycardia [1]. Labetalol (La) is also an antihypertensive agent with α and β advenergic blocking activity [2], but how it affects intracranial pressure in comparison to SNP has yet to be determined. We, therefore, compared the effect of La and SNP on the intracranial pressure and heart rate of cats.

Keywords

Catheter Dioxide Isoflurane Toxicology Nitroprusside 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Tinker JH, Michenfelder JD (1976) Sodium nitroprusside: Pharmacology, toxicology and therapeutics. Anesthesiology 45:340–54PubMedCrossRefGoogle Scholar
  2. 2.
    Weiner N (1975) Drugs that inhibit advenergic nerves and block advenergic receptors. The Pharmacological Basis of Therapeutics. In: Gilman AG, Goodman LS, Gilman A (eds) MacMillan Publishing, p. 197Google Scholar
  3. 3.
    Ganong WF (1987) Circulation through special regions. In: Ganong WF (eds) Review of medical physiology, Lange, CaliforniaGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • S. Thiagarajah
    • 1
  • E. Lear
    • 1
  • I. Azar
    • 1
  1. 1.Beth Israel Medical CenterNew YorkUSA

Personalised recommendations