Histopathology of Human Lyme Borreliosis

  • J. De Koning
  • P. H. Duray


Lyme borreliosis is a disorder affecting many organs including the skin and reticuloendothelial, cardiovascular, nervous and musculoskeletal systems. The causative organism is Borrelia burgdorferi. After infection via a tick bite, a series of events follows in an attempt to destroy the microorganisms or limit its spread to other sites. The early skin lesion around the tickbite shows edema, vascular dilatation, extravasation of erythrocytes and an inflammatory infiltrate of neutrophils. If the causative organisms persist in the skin, the infiltrate shows predominantly lymphocytes and in many circumstances plasma cells.


Plasma Cell Lyme Disease Borrelia Burgdorferi Lyme Borreliosis Lymphocytic Infiltrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • J. De Koning
  • P. H. Duray

There are no affiliations available

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